Simultaneous determination of norepinephrine, serotonin, and 5-hydroxyindole-3-acetic acid in microdialysis samples from rat brain by microbore column liquid chromatography with fluorescence detection following derivatization with benzylamine
Yoshitake T, et al.
Analytical Biochemistry, 312(2), 125-133 (2003)
The Derivatization of Proquinoidal Analytes with 1, 2-Diphenylethane-1, 2-Diamine (DPE) and Benzylamine (BA): An Investigation of Products, Yields, Kinetics and Reagent Selectivity
Woods JM, et al.
Chromatographia, 78(3-4), 163-178 (2015)
Kaoru Fujino et al.
Journal of chromatography. A, 1012(2), 169-177 (2003-10-03)
A highly selective and sensitive method for the simultaneous determination of 5-hydroxyindoles and catechols (serotonin, norepinephrine, dopamine and related compounds) by high-performance liquid chromatography with fluorescence detection is described. The method is based on the two-step precolumn derivatization of 5-hydroxyindoles...
Hong Cao et al.
Organic letters, 13(1), 11-13 (2010-12-02)
A versatile synthesis of unsaturated seven-membered ring lactams has been developed. The sequence involves hydroamination of Baylis-Hillman acetate with amines, followed by intramolecular cyclocarbonylation reactions of the resulting allylamines. This process can tolerate a wide array of functional groups, and...
Fei Mao et al.
Bioorganic & medicinal chemistry, 20(19), 5884-5892 (2012-09-05)
In an effort to identify novel multifunctional drug candidates for the treatment of Alzheimer's disease (AD), a series of hybrid molecules were synthesised by reacting N-(aminoalkyl)tacrine with salicylic aldehyde or derivatives of 2-aminobenzaldehyde. These compounds were then evaluated as multifunctional...