15256

BSA+TMCS

for GC derivatization, LiChropur^™, 93.0-97.0% (GC)

• Synonym(s): Bis(trimethylsilyl)acetamide + Trimethylchlorosilane
• UNSPSC Code: 41116105
• PubChem Substance ID: 24849236
• NACRES: NA.22

Properties

• grade: for GC derivatization
• Quality Level: 100
• assay: 93.0-97.0% (GC)
• quality: LiChropur^™
• composition: trimethylchlorosilane (minor component), 3.0-5.0% GC
• reaction suitability: reagent type: derivatization reagent; reaction type: Silylations
• technique(s): gas chromatography (GC): suitable

Description

General description

BSA+TMCS combination, is one of the most commonly used silylating reagents. BSA is readily used for silylating a wide range of functional groups such as non-sterically hindered alcohols, amides, amines, amino acids, carboxylic acids, and enols. TMCS is a silylation catalyst always used with other silylation reagents to increase the reactivity in derivatization of alcohols, alkaloids, amines, biogenic amines, carboxylic acids, phenols, and steroids.

Application

Learn more in the Product Information

Suitable for the derivatization of α-ketoacids, amines, amino acids, cycloserine, histamine and metabolites, phenylethylamines, phosphatidylserines and tryptamines. BSA+TMCS may be used as a derivatizing reagent for the determination of steryl glycosides in biodiesel using gas chromatography–mass spectrometry.[1]

Suitable for the derivatization of a-ketoacids, amines, amino acids, cycloserine, histamine and metabolites, phenylethylamines, phosphatidylserines and tryptamines.

Features and Benefits

• BSA+TMCS has good solvent properties and can function as a silylation reagent without additional solvents.        
• Alternatively, the mixture is very soluble in most commonly used silylation solvents.        
• This combination is extremely sensitive to moisture and should be handled under dry conditions.

Other Notes

Powerful silylation mixture with wide applicability[2][3][4]

Reagent for trimethylsilyl diglyceride, trimethylsilyl (TMS) and trimethylsilyl oximes.

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS02,GHS05,GHS07
• signalword: Danger
• hcodes: H225,H302,H314
• pcodes: P210 - P233 - P264 - P303 + P361 + P353 - P370 + P378 - P403 + P235
• Hazard Classifications: Acute Tox. 4 Oral - Flam. Liq. 2 - Skin Corr. 1A
• supp_hazards: EUH014
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 53.6 °F - closed cup
• flash_point_c: 12 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter