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Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(4), 1005-1015 (2014-10-21)
Successful decision making often requires weighing a given option's costs against its associated benefits, an ability that appears perturbed in virtually every severe mental illness. Animal models of such cost/benefit decision making overwhelmingly implicate mesolimbic dopamine in our willingness to...
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Molecular neurodegeneration, 9, 53-53 (2014-11-25)
Synaptic degeneration is an early pathogenic event in Alzheimer's disease, associated with cognitive impairment and disease progression. Cerebrospinal fluid biomarkers reflecting synaptic integrity would be highly valuable tools to monitor synaptic degeneration directly in patients. We previously showed that synaptic...