18588

Cefixime trihydrate

suitable for microbiology, ≥98.0% (HPLC)

• Empirical Formula (Hill Notation): C₁₆H₁₅N₅O₇S₂ · 3H₂O
• CAS Number: 125110-14-7
• Molecular Weight: 507.50
• NACRES: NB.61
• PubChem Substance ID: 329751717
• UNSPSC Code: 26111700
• MDL number: MFCD03788802

Properties

• InChI: 1S/C16H15N5O7S2.3H2O/c1-2-6-4-29-14-10(13(25)21(14)11(6)15(26)27)19-12(24)9(20-28-3-8(22)23)7-5-30-16(17)18-7;;;/h2,5,10,14H,1,3-4H2,(H2,17,18)(H,19,24)(H,22,23)(H,26,27);3*1H2/b20-9-;;;/t10-,14-;;;/m1.../s1
• SMILES string: O.O.O.Nc1nc(cs1)C(=N\OCC(O)=O)\C(=O)N[C@H]2[C@H]3SCC(C=C)=C(N3C2=O)C(O)=O
• InChI key: IPYWNMVPZOAFOQ-NABDTECSSA-N
• description: for ion-selective electrodes
• assay: ≥98.0% (HPLC)
• antibiotic activity spectrum: Gram-negative bacteria, Gram-positive bacteria
• application(s): microbiology
• mode of action: cell wall synthesis | interferes
• Quality Level: 100

Description

Analysis Note

Soluble in methanol and propylene glycol; slightly soluble in alcohol in acetone and in glycerin; very slightly soluble in 70% sorbitol and in octanol; practically insoluble in ether, in ethyl acetate, in hexane and in water

Application

• Physicochemical parameters and modes of interaction associated with the micelle formation of a mixture of tetradecyltrimethylammonium bromide and cefixime trihydrate: effects of hydrotropes and temperature.: This research delves into the physicochemical behaviors of cefixime trihydrate when mixed with tetradecyltrimethylammonium bromide, focusing on micelle formation and the influence of various hydrotropes and temperature changes on their interaction (Hossain M et al., 2023).


• Development, validation and greenness assessment of a new electro-driven separation method for simultaneous analysis of cefixime trihydrate and linezolid in their fixed dose combination.: This study introduces and validates a novel eco-friendly electro-driven method for analyzing cefixime trihydrate in combination with linezolid, emphasizing its application in fixed-dose pharmaceutical formulations (Habeeb MR et al., 2023).


• Bioremediation of multifarious pollutants using laccase immobilized on magnetized and carbonyldiimidazole-functionalized cellulose nanofibers.: Investigates the efficacy of laccase enzymes, immobilized on specialized cellulose nanofibers, in the bioremediation of pollutants, a process applicable to the environmental management of pharmaceutical agents including cefixime trihydrate (Sharma K et al., 2023).

General description

Chemical structure: β-lactam

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Other Notes

Determination of ytterbium in mineral probes (e.g. Zeolith-catalysts, Xenotime,...)[1]

Safety Information

• pictograms: GHS08
• signalword: Danger
• hcodes: H317,H334
• pcodes: P261 - P280 - P342 + P311
• Hazard Classifications: Resp. Sens. 1 - Skin Sens. 1
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves