222488

Sigma-Aldrich

N-(1-Naphthyl)ethylenediamine dihydrochloride

ACS reagent, >98%

Synonym(s):
2-(1-Naphthylamino)ethylamine dihydrochloride
Linear Formula:
C10H7NHCH2CH2NH2 · 2HCl
Molecular Weight:
259.17
Beilstein/REAXYS Number:
3707471
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

Quality Level

grade

ACS reagent

assay

>98%

impurities

≤5% water

mp

194-198 °C (dec.) (lit.)

solubility

H2O: passes test

suitability

passes test for sensitivity to sulfanilamide

SMILES string

Cl.Cl.NCCNc1cccc2ccccc12

InChI

1S/C12H14N2.2ClH/c13-8-9-14-12-7-3-5-10-4-1-2-6-11(10)12;;/h1-7,14H,8-9,13H2;2*1H

InChI key

MZNYWPRCVDMOJG-UHFFFAOYSA-N

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General description

N-(1-Naphthyl)ethylenediamine dihydrochloride (NEDA·2HCl) acts as donor molecule and forms charge transfer (CT) complexes with π-acceptors (quinol and picric acid), σ-acceptors (iodine) and vacant orbital acceptors (tin(IV) tetrachloride and zinc chloride). These complexes were investigated by positron annihilation lifetime spectroscopy (PAL).

Application

Solution of N-(1-naphthyl)ethylenediamine dihydrochloride in sulfuric acid-methanol may be employed for the quantitation of sugars.
N-(1-Naphthyl)ethylenediamine dihydrochloride may be used in the synthesis of 5-[1,2]dithiolan-3-yl-pentanoic acid [2-(naphthalene-1-ylamino)-ethyl]amide (DPAN) by reacting with (±)-1,2-dithiolane-3-pentanoic acid in the presence of N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride and N-hydroxysuccinimide. The solution formed by dissolving N-(1-naphthyl)ethylenediamine dihydrochloride in sulfuric acid-methanol may be used as a reagent for the detection of sugars at nanoscale on thin-layer plates.
N-(1-Naphthyl)ethylenediamine dihydrochloride has been used for the preparation of staining solution for the visualization of the reaction product(s) of starch active enzymes, containing α-1, 4 linked and α-1, 6 linked glucose by thin layer chromatography. It has also been used in modified Saville and Griess assays.
Coupling agent for the spectrophotometric determination of aminophenols, phenylenediamines, dinitroanilines, chloroanilines, thiols, and sulfonamides.

Packaging

5, 10, 25, 100, 500 g in glass bottle

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Functionalization of platinum nanoparticles for electrochemical detection of nitrite.
Miao P, et al.
Analytical and Bioanalytical Chemistry, 399(7), 2407-2411 (2011)
Moamen S Refat et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 122, 34-47 (2013-12-03)
In this work, structural, thermal, morphological, pharmacological screening and positron annihilation lifetime measurements were performed on the interactions between a N-(1-Naphthyl)ethylenediamine dihydrochloride (NEDA·2HCl) donor and three types of acceptors to characterize these CT complexes. The three types of acceptors include...
Analytica Chimica Acta, 204, 271-271 (1988)
N-(1-naphthyl)ethylenediamine dihydrochloride as a new reagent for nanomole quantification of sugars on thin-layer plates by a mathematical calibration process.
M Bounias
Analytical biochemistry, 106(2), 291-295 (1980-08-01)
Analytical Chemistry, 55, 1226-1226 (1983)

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