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242888

Sigma-Aldrich

Tetrahydrofuran

spectrophotometric grade, ≥99.5%, inhibitor-free

Synonym(s):
Tetramethylene oxide, THF, Oxolane, Butylene oxide
Empirical Formula (Hill Notation):
C4H8O
CAS Number:
Molecular Weight:
72.11
Beilstein:
102391
EC Number:
MDL number:
PubChem Substance ID:

grade

spectrophotometric grade

vapor density

2.5 (vs air)

vapor pressure

114 mmHg ( 15 °C)
143 mmHg ( 20 °C)

assay

≥99.5%

form

liquid

autoignition temp.

610 °F

expl. lim.

1.8-11.8 %

application(s)

UV/Vis spectroscopy: suitable

impurities

≤0.015% peroxide (as H2O2)
<0.02% water

evapn. residue

<0.0005%

refractive index

n20/D 1.407 (lit.)

bp

65-67 °C (lit.)

mp

−108 °C (lit.)

density

0.889 g/mL at 25 °C (lit.)

λ

H2O reference

UV absorption

λ: 212 nm Amax: 1.0
λ: 250 nm Amax: 0.18
λ: 300 nm Amax: 0.02
λ: 350-400 nm Amax: 0.005

SMILES string

C1CCOC1

InChI

1S/C4H8O/c1-2-4-5-3-1/h1-4H2

InChI key

WYURNTSHIVDZCO-UHFFFAOYSA-N

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Other Notes

A -D suffix exists for administrative purposes only.
All -D packages are 100% the same product, same quality, same specification as the package sizes previously sold without a -D.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Luca Chiari et al.
The Journal of chemical physics, 138(7), 074301-074301 (2013-03-01)
We present total, elastic, and inelastic cross sections for positron and electron scattering from tetrahydrofuran (THF) in the energy range between 1 and 5000 eV. Total cross sections (TCS), positronium formation cross sections, the summed inelastic integral cross sections (ICS)...
Crispin Lichtenberg et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 21(44), 15797-15805 (2015-09-17)
The reactivity of the all-ferrous FeN heterocubane [Fe4 (Ntrop)4 ] (1) with i) Brønsted acids, ii) σ-donors, iii) σ-donors/π-acceptors, and iv) one-electron oxidants has been investigated (trop = 5H-dibenzo[a,d]cyclo-hepten-5-yl). 1 showed self-re-assembling after reactions with i) and proved surprisingly inert in reactions with ii)...
C N Ong et al.
British journal of industrial medicine, 48(9), 616-621 (1991-09-01)
Occupational exposure to tetrahydrofuran (THF) was studied by analysis of environmental air, blood, alveolar air, and urine from 58 workers in a video tape manufacturing plant. Head space gas chromatography (GC) with an FID detector was used for determination of...
Kenneth F Ilett et al.
Drug metabolism and disposition: the biological fate of chemicals, 30(9), 1005-1012 (2002-08-09)
The aim of this study was to elucidate the metabolic pathways for dihydroartemisinin (DHA), the active metabolite of the artemisinin derivative artesunate (ARTS). Urine was collected from 17 Vietnamese adults with falciparum malaria who had received 120 mg of ARTS...
Eliane M de Oliveira et al.
Physical chemistry chemical physics : PCCP, 15(5), 1682-1689 (2012-12-19)
We report elastic integral, differential and momentum transfer cross sections for low-energy electron scattering by the cellulose components β-D-glucose and cellobiose (β(1 → 4) linked glucose dimer), and the hemicellulose component β-D-xylose. For comparison with the β forms, we also...

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