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247588

Salicylic acid

ACS reagent grade, ≥99.0%

Synonym(s):

2-Hydroxybenzoic acid

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100 g
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$52.90
500 g
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$109.00

About This Item

Linear Formula:
2-(HO)C6H4CO2H
CAS Number:
Molecular Weight:
138.12
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
200-712-3
MDL number:
Beilstein/REAXYS Number:
774890
Assay:
≥99.0%

$52.90


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Product Name

Salicylic acid, ACS reagent, ≥99.0%

grade

ACS reagent

Quality Segment

vapor density

4.8 (vs air)

vapor pressure

1 mmHg ( 114 °C)

assay

≥99.0%

impurities

H2SO4, passes test (darkened)

ign. residue

≤0.01%

bp

211 °C (lit.)

mp

158-161 °C (lit.)

anion traces

chloride (Cl-): ≤0.001%, sulfate (SO42-): ≤0.003%

cation traces

Fe: ≤2 ppm, heavy metals (as Pb): ≤5 ppm

functional group

carboxylic acid

SMILES string

OC(=O)c1ccccc1O

InChI

1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)

InChI key

YGSDEFSMJLZEOE-UHFFFAOYSA-N

Gene Information

human ... ALB(213), PTPN1(5770)

General description

Salicylic acid is mainly used as the precursor to synthesize aspirin, a commonly used analgesic and antipyretic. Due to its keratolytic action, it is also used in topical ointments.

Application

Salicylic acid has been used:
  • as one of the chemical compound in exposure-based validation of in vitro gastrulation model employed in developmental toxicity screening assays
  • as a reference standard in salicylate quantification by reverse-phase high-performance liquid chromatography (RP-HPLC)

Biochem/physiol Actions

Salicylic acid (SA) delivers local and systemic acquired resistance (LAR and SAR) against various diseases in plants. It acts as a secondary metabolite and regulate various physiological processes such as respiration, stomatal closure and senescence-associated gene expression. In addition, SA also controls abiotic stress, basal thermotolerance, nodulation in legumes and fruit yield. It plays a vital role in modulation of flowering and thermogenesis (heat production) in plants. SA together with reactive oxygen species (ROS) and nitric oxide (NO) triggers cell death in plants.

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This Item
S74015234127301
description

ACS reagent, ≥99.0%

description

suitable for plant cell culture

description

certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

description

meets analytical specification of Ph. Eur., BP, USP, 99.5-100.5% (calc. to the dried substance)

assay

≥99.0%

assay

≥99% (HPLC)

assay

-

assay

99.5-100.5% (calc. to the dried substance)

Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

200

bp

211 °C (lit.)

bp

211 °C (lit.)

bp

211 °C (lit.)

bp

211 °C (lit.)

mp

158-161 °C (lit.)

mp

158-161 °C (lit.)

mp

158-161 °C (lit.)

mp

158-161 °C

vapor density

4.8 (vs air)

vapor density

4.8 (vs air)

vapor density

4.8 (vs air)

vapor density

4.8 (vs air)

ign. residue

≤0.01%

ign. residue

-

ign. residue

-

ign. residue

≤0.05% (as SO4)


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signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

314.6 °F - closed cup

flash_point_c

157 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Can I use this reagent for treatment of plantar wart?

    1 answer
    1. This product is intended for laboratory research purposes only. This product not to be used for any other purposes, including but not limited to, in vitro diagnostic purposes, in foods, drugs, medical devices or cosmetics for humans or animals or for commercial purposes.

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