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255564

Sigma-Aldrich

L-Ascorbic acid

ACS reagent, ≥99%

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Synonym(s):
L-Threoascorbic acid, Antiscorbutic factor, Vitamin C
Empirical Formula (Hill Notation):
C6H8O6
CAS Number:
Molecular Weight:
176.12
Beilstein/REAXYS Number:
84272
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

grade

ACS reagent

Quality Level

assay

≥99%

form

crystals or granules
powder or chunks

optical activity

[α]25/D +20.5 to +21.5° in H2O

technique(s)

HPLC: suitable
cell culture | mammalian: suitable

ign. residue

<0.1%

color

white

pH

1.0-2.5 (25 °C, 176 g/L in water)

mp

190-194 °C (dec.)

solubility

water: soluble 176 g/L at 20 °C

cation traces

Fe: ≤0.001%
heavy metals: ≤0.002% (by ICP-OES)

application(s)

cell analysis

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Gene Information

human ... SLC23A2(9962)

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1 of 4

This Item
7954373303495210
vibrant-m

255564

L-Ascorbic acid

vibrant-m

795437

L-Ascorbic acid

vibrant-m

33034

L-Ascorbic acid

vibrant-m

95210

L-Ascorbic acid

assay

≥99%

assay

≥99%

assay

99.7-100.5% (oxidimetric)

assay

≥99.0% (RT)

technique(s)

HPLC: suitable, cell culture | mammalian: suitable

technique(s)

-

technique(s)

IR spectroscopy: suitable

technique(s)

-

form

chunks, crystals, powder, crystalline powder, granular

form

powder

form

solid

form

powder or crystals (possibly with chunks)

solubility

water: soluble 176 g/L at 20 °C

solubility

water: soluble 176 g/L at 20 °C

solubility

water: soluble 176 g/L at 20 °C

solubility

H2O: 50 mg/mL at 20 °C, clear, almost colorless

application(s)

cell analysis

application(s)

-

application(s)

cell analysis

application(s)

-

General description

L-Ascorbic acid or vitamin C is a water-soluble vitamin found in various foodstuffs. Benefits of vitamin C may include protection against immune system deficiencies, cardiovascular disease, hyperpigmentation, skin protection, anti-aging, iron absorption, and red blood cell production. It is also useful in the biosynthesis of collagen, L-carnitine, and neurotransmitters.

Application

L-ascorbic acid (L-AA) can be used as a reducing as well as a capping agent in the synthesis of well-dispersed metal nanoparticles and also in the reduction of graphene oxide sheets.
Its immunostimulant derivatives play an important role in cell regulation.

Legal Information

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Synthesis of highly stable dispersions of nanosized copper particles using L-ascorbic acid
Xiong J, et al.
Green Chemistry, 13(4), 900-904 (2011)
Acta Biochimica et Biophysica Hungarica, 22, 167-167 (1987)
Vitamin C: One compound, several uses. Advances for delivery, efficiency and stability
Carita AC, et al.
Nanomedicine: Nanotechnology, Biology, and Medicine, 31(2), 102117-102117 (2019)
A review of micronutrients in sepsis: the role of thiamine, l-carnitine, vitamin C, selenium and vitamin D
Belsky JB, et al.
Nutrition Research Reviews, 31(2), 281-290 (2018)
Vitamin c
Linster CL and Van SE
FEBS Journal, 274(1), 1-22 (2007)

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