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29992

DL-α-Tocopherol acetate

tested according to Ph. Eur.

Synonym(s):

α-Tocopherylis acetas, Vitamin E acetate, all-rac-α-Tocopheryl acetate

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50 G

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About This Item

Empirical Formula (Hill Notation):
C31H52O3
CAS Number:
7695-91-2
Molecular Weight:
472.74
UNSPSC Code:
12352209
NACRES:
NA.26
PubChem Substance ID:
329753404
EC Number:
231-710-0
Beilstein/REAXYS Number:
97512
MDL number:
MFCD00072042

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SMILES string

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1

InChI

1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1

InChI key

ZAKOWWREFLAJOT-CEFNRUSXSA-N

biological source

synthetic

Quality Level

200

agency

tested according to Ph. Eur.

assay

96.5-102.0%

form

liquid

density

0.96 g/mL at 20 °C (lit.)

application(s)

cell analysis
research use (small molecule)

storage temp.

2-8°C

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This Item
T33769235947786
DL-α-Tocopherol acetate tested according to Ph. Eur.

Sigma-Aldrich

29992

DL-α-Tocopherol acetate

DL-α-Tocopherol acetate ≥96% (HPLC)

Sigma-Aldrich

T3376

DL-α-Tocopherol acetate

DL-α-Tocopherol acetate certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Supelco

92359

DL-α-Tocopherol acetate

DL-alpha-Tocopherol acetate analytical standard

Supelco

47786

DL-alpha-Tocopherol acetate

biological source

synthetic

biological source

synthetic (organic)

biological source

-

biological source

-

assay

96.5-102.0%

assay

≥96% (HPLC)

assay

-

assay

-

form

liquid

form

viscous liquid

form

viscous liquid

form

-

application(s)

cell analysis
pharmaceutical (small molecule)

application(s)

-

application(s)

vitamins, nutraceuticals, and natural products

application(s)

pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-10 to -25°C

Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

100

General description

α-Tocopherol is a form of vitamin E.[1] Vitamin E can be obtained through dietary sources.[2] RRR‐α‐tocopherol is a natural form of α-Tocopherol.[3]

Application

DL-alpha-Tocopherol acetate was used as a vitamin E supplement for studying whether the addition of an antioxidant or vitamin E in the diet of rats with dextran sulfate sodium (DSS)-induced colitis can reduce detrimental impact of inflammatory bowel disease.[4]

Biochem/physiol Actions

α-Tocopherol is also known as a radical-chain breaker due to its anti-oxidant property.[5]
Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by Homosapiens. DL-α-Tocopherol acetate can inhibit oxidation of linoleate.[6]

Storage Class

10 - Combustible liquids

flash_point_f

No data available

flash_point_c

No data available

ppe

Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN5609
BCCM9427
BCCL6301
BCCK1975
BCCJ1557

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S Grossman et al.
The International journal of biochemistry, 16(3), 281-289 (1984-01-01)
The formation of alpha-tocopherol--lipoxygenase complex was elucidated using immobilized affinity purified soybean lipoxygenase and [D-3H]alpha-tocopherol. The alpha-tocopherol--lipoxygenase complex did not dissociate on addition of linoleic acid. Iodoacetate modified immobilized lipoxygenase did not form the complex with alpha-tocopherol. Lipoxygenase attached to
Julie Carrier et al.
The Journal of nutrition, 132(10), 3146-3150 (2002-10-09)
Inflammatory bowel disease is often associated with iron deficiency anemia and oral iron supplementation may be required. However, iron may increase oxidative stress through the Fenton reaction and thus exacerbate the disease. This study was designed to determine in rats
alpha-Tocopherol stereoisomers
Jensen S K and Lauridsen C
Vitamins and Hormones, 76(3), 281-308 (2007)
Vitamin E supplementation and cardiovascular events in high-risk patients.
Yusuf S, et al.
The New England Journal of Medicine, 342(3), 154-160 (2000)
Absorption, transport, and tissue delivery of vitamin E
Rigotti A
Molecular Aspects of Medicine, 28(5-6), 423-436 (2007)
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Articles

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

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