30050

Sigma-Aldrich

Cystamine dihydrochloride

purum, ≥98.0% (AT)

Synonym(s):
Decarboxycystine dihydrochloride, 2,2′-Diaminodiethyl disulfide dihydrochloride, 2,2′-Dithiobis(ethylamine) dihydrochloride
Linear Formula:
NH2CH2CH2SSCH2CH2NH2 · 2HCl
CAS Number:
Molecular Weight:
225.20
Beilstein/REAXYS Number:
3616850
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

grade

purum

assay

≥98.0% (AT)

mp

217-220 °C (dec.) (lit.)
~220 °C (dec.)

solubility

water: soluble 1 g/10 mL, clear, colorless

SMILES string

Cl[H].Cl[H].NCCSSCCN

InChI

1S/C4H12N2S2.2ClH/c5-1-3-7-8-4-2-6;;/h1-6H2;2*1H

InChI key

YUFRRMZSSPQMOS-UHFFFAOYSA-N

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Related Categories

Application

Cystamine dihydrochloride was used:
  • as sulfhydryl modifying reagent
  • in synthesis of monoclonal anti-prostate-specific membrane antigen antibody and A9 RNA aptamers-conjugated popcorn shape gold nanoparticles
  • as internal standard in determination of total homocysteine
  • in modification of gold nanorod surface by amine groups

Other Notes

Sulfhydryl modifying reagent

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

hazcat

Acute Tox. 4 Oral

storage_class_code

13 - Non Combustible Solids

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Anant K Singh et al.
ACS nano, 3(7), 1906-1912 (2009-07-04)
The presence of E. coli in foodstuffs and drinking water is a chronic worldwide problem. The worldwide food production industry is worth about U.S. $578 billion, and the demand for biosensors to detect pathogens and pollutants in foodstuffs is growing...
L J Riddell et al.
The American journal of clinical nutrition, 71(6), 1448-1454 (2000-06-06)
Elevated plasma total homocysteine (tHcy) concentrations are associated with increased risk of vascular disease, and there is a strong inverse association between dietary and blood folate and blood tHcy concentrations. Increased folate consumption may lower the risk of tHcy-mediated cardiovascular...
Wentong Lu et al.
Journal of the American Chemical Society, 132(51), 18103-18114 (2010-12-07)
Prostate cancer is the second leading cause of cancer-related death among the American male population, and the cost of treating prostate cancer patients is about $10 billion/year in the United States. Current treatments are mostly ineffective against advanced-stage prostate cancer...
Nan-Fu Chiu et al.
International journal of nanomedicine, 14, 4833-4847 (2019-07-17)
The use of functionalized graphene oxide (fGO) has led to a new trend in the sensor field, owing to its high sensitivity with regards to sensing characteristics and easy synthesis procedures. In this study, we developed an ultra-sensitive carboxyl-graphene oxide...
Zhengjie Yang et al.
Journal of orthopaedic translation, 21, 57-65 (2020-02-27)
The survival rate of osteosarcoma therapy still lags behind overall cancer therapies due to the intrinsic or acquired drug resistance. Developing novel drug delivery systems that may overcome drug resistance would greatly facilitate osteosarcoma therapy. Poly(ethylene glycol) (PEG)-sheddable reduction-sensitive polyurethane...

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