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31097

Supelco

1-Naphthol

PESTANAL®, analytical standard

Synonym(s):
α-Naphthol, 1-Hydroxynaphthalene
Linear Formula:
C10H7OH
CAS Number:
Molecular Weight:
144.17
Beilstein:
1817321
EC Number:
MDL number:
PubChem Substance ID:

Quality Level

grade

analytical standard

vapor density

4.5 (120 °C, vs air)

vapor pressure

1 mmHg ( 94 °C)

product line

PESTANAL®

assay

≥98.0% (GC)

form

neat

autoignition temp.

1007 °F

shelf life

limited shelf life, expiry date on the label

expl. lim.

5 %

application(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

278-280 °C (lit.)

mp

94-96 °C (lit.)

Featured Industry

Forensics and Toxicology
Pharmaceutical (small molecule)

format

neat

SMILES string

Oc1cccc2ccccc12

InChI

1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H

InChI key

KJCVRFUGPWSIIH-UHFFFAOYSA-N

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General description

1-Naphthol, a metabolite of carbaryl and naphthanlene. It is formed by spontaneous reaction from (1R, 2S)-Naphthalene epoxide followed to form 1, 4-Dihydroxynaphthalene.

Application

1-Naphthol may be used as a reference standard for the determination of 1-naphthol:
  • In human urine by a rapid and automated method based on coupled-column liquid chromatography (LC-LC) with fluorescence detection.
  • In canned fruit juices by reversed-phase high performance liquid chromatography with diode-array detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Sigma-Aldrich International GmbH

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1A - STOT SE 2 Oral - STOT SE 3

Target Organs

Kidney, Respiratory system

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK Germany

WGK 1

Flash Point(F)

257.0 °F - closed cup

Flash Point(C)

125 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

A Simple Method for the Determination of Carbaryl and 1-Naphthol in Fruit Juices by High-Performance Liquid Chromatography- Diode-Array Detection.
Sancho JV, et al.
Journal of Food Protection, 66(8), 1510- 1513 (2003)
Direct determination of 1-naphthol in human urine by coupled-column liquid chromatography with fluorescence detection.
Sancho JV, et al.
Chromatographia, 58(9-10), 565- 569 (2003)
Ondrej Zitka et al.
Electrophoresis, 32(22), 3207-3220 (2011-10-21)
Guanosine derivatives are important for diagnosis of oxidative DNA damage including 8-hydroxy-2'-deoxyguanosine (8-OHdG) as one of the most abundant products of DNA oxidation. This compound is commonly determined in urine, which makes 8-OHdG a good non-invasive marker of oxidation stress....
Hongbo Zhang et al.
Toxicology in vitro : an international journal published in association with BIBRA, 26(8), 1286-1293 (2012-01-24)
In vitro glucuronidation assays of diclofenac and indomethacin at pH 7.4 are biased by the instability of the glucuronides due to acyl migration. The extent of this acyl migration may be reduced significantly by performing the glucuronidation reaction at pH...
Shitong Yang et al.
The Science of the total environment, 420, 214-221 (2012-02-15)
The increasing exploitation of multi-walled carbon nanotubes (MWCNTs) into many industrial processes has raised considerable concerns as they are likely to be released into the environment. The interactions of the pollutants in water with discharged MWNCTs will further influence the...

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