31564

Supelco

Acrylonitrile

analytical standard

Synonym(s):
Vinyl cyanide
Linear Formula:
CH2=CHCN
CAS Number:
Molecular Weight:
53.06
Beilstein/REAXYS Number:
605310
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

Quality Level

grade

analytical standard

vapor density

1.83 (vs air)

vapor pressure

86 mmHg ( 20 °C)

assay

≥98% (GC)

form

neat

autoignition temp.

897 °F

quality

stabilized

shelf life

limited shelf life, expiry date on the label

expl. lim.

17 %

application(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.391 (lit.)

bp

77 °C (lit.)

mp

−83 °C (lit.)

Featured Industry

Cleaning Products
Cosmetics
Environmental
Food and Beverages
Personal Care

format

neat

storage temp.

2-8°C

SMILES string

C=CC#N

InChI

1S/C3H3N/c1-2-3-4/h2H,1H2

InChI key

NLHHRLWOUZZQLW-UHFFFAOYSA-N

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General description

Acrylonitrile (AN) is a volatile liquid mostly used in manufacturing plastics and polymers.

Application

AN may have been used as standard during headspace gas chromatography for the determination of AN monomer in plastic containers and carbonated beverages.
Acrylonitrile is used in the manufacture of acrylic fibers, resins (acrylonitrile butadiene-styrene, styrene-acrylonitrile and others) and nitrile rubbers (butadiene-acrylonitrile).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

An industrial carcinogen that is a multisite carcinogen in rats and possibly carcinogenic to humans.

Signal Word

Danger

Target Organs

Respiratory system

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

UN1093 - class 3 - PG 1 - Acrylonitrile, stabilized

WGK Germany

WGK 3

Flash Point(F)

23.0 °F - closed cup

Flash Point(C)

-5 °C - closed cup

Certificate of Analysis

Certificate of Origin

Role of cytochrome P450 2E1 in the metabolism of acrylamide and acrylonitrile in mice.
Sumner SC
Chemical Research in Toxicology, 12(11), 1110-1116 (1999)
Determination of acrylonitrile monomer in plastic packaging and beverages by headspace gas chromatography.
Gawell, GB-M.
Analyst, 104.1235, 106-110 (1979)
A Léonard et al.
Mutation research, 436(3), 263-283 (1999-06-04)
Acrylonitrile (AN) is an important intermediary for the synthesis of a variety of organic products, such as artificial fibres, household articles and resins. Although acute effects are the primary concern for an exposure to AN, potential genotoxic, carcinogenic and teratogenic...
J Whysner et al.
Regulatory toxicology and pharmacology : RTP, 27(3), 217-239 (1998-08-07)
Acrylonitrile (ACN) exposure is associated with tumors in rat brain, Zymbal gland, and mammary gland. Adducts affecting base pairing were formed in isolated DNA exposed in vitro to the ACN metabolite cyanoethylene oxide (CNEO). DNA from liver, which is not...
Philip Cole et al.
Regulatory toxicology and pharmacology : RTP, 52(3), 342-351 (2008-10-18)
Several retrospective cohort epidemiology studies evaluated a number of health outcomes in workers exposed to acrylonitrile (AN). The epidemiology studies included in this review have been published since 1970 and were identified through Ovid and MEDLINE retrieval services using search...

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