Amoxicillin trihydrate

VETRANAL®, analytical standard

Empirical Formula (Hill Notation):
C16H19N3O5S · 3H2O
CAS Number:
Molecular Weight:
Beilstein/REAXYS Number:
MDL number:
PubChem Substance ID:
Pricing and availability is not currently available.

Quality Level


analytical standard

product line




shelf life

limited shelf life, expiry date on the label


HPLC: suitable
gas chromatography (GC): suitable

Featured Industry

Forensics and Toxicology
Pharmaceutical (small molecule)



storage temp.


SMILES string




InChI key


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General description

Amoxicillin trihydrate is a β-lactam antibiotic. It is a broad-spectrum drug mostly administered orally.1 It is used to treat bacterial infections mainly caused by susceptible microorganisms.2
Chemical structure: ß-lactam


Commission Regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin
Amoxicillin trihydrate may be used as reference standard in stability study of Amoxicillin-Clavulanate in BACTEC Medium performed using HPLC.3
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Sigma-Aldrich Chemie GmbH


Health hazard

Signal Word


Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves


NONH for all modes of transport

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Claudia Foti et al.
Molecules (Basel, Switzerland), 25(14) (2020-07-12)
A potentiometric and UV spectrophotometric investigation on Mn2+-ampicillin and Mn2+-amoxicillin systems in NaCl aqueous solution is reported. The potentiometric measurements were carried out under different conditions of temperature (15 ≤ t/°C ≤ 37). The obtained speciation pattern includes two species...
Yu-Hsin Lin et al.
Biomaterials, 34(18), 4466-4479 (2013-03-19)
Helicobacter pylori is a significant human pathogen that recognizes specific carbohydrate receptors, such as the fucose receptor, and produces the vacuolating cytotoxin, which induces inflammatory responses and modulates the cell-cell junction integrity of the gastric epithelium. The clinical applicability of...
Fanny B Morel et al.
Neonatology, 103(3), 182-189 (2013-02-26)
It is suggested that antibiotherapy in infancy might program adult body composition and thus could be a determinant of obesity risk. Although not convincingly substantiated by existing literature, this assumption is plausible since antibiotics affect intestinal microbiota, whose composition in...
Qian Zhao et al.
Water science and technology : a journal of the International Association on Water Pollution Research, 67(7), 1605-1611 (2013-04-05)
This paper investigated the effects of selected common chemical species in natural waters (HCO3(-), NO3(-) and humic acids (HA)) on the photodegradation of amoxicillin (AMO) under simulated irradiation using a 300 W xenon lamp. Quenching experiments were carried out to...
Adriaan Blommaert et al.
The Journal of antimicrobial chemotherapy, 68(10), 2383-2392 (2013-05-18)
Bacterial resistance to antibiotics, driven by antibiotic consumption, imposes a major threat to the effective treatment of bacterial infections. In addition to reducing the amount of antibiotics prescribed, avoiding broad-spectrum antibiotics could extend the lifetime of the current arsenal of...

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