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31593

Supelco

Arecoline hydrobromide

VETRANAL®, analytical standard

Synonym(s):
Methyl 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylate hydrobromide, 1-Methyl-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid methyl ester hydrobromide, Taeniolin, Arecaidine methyl ester hydrobromide, Methyl 1-methyl-1,2,5,6-tetrahydronicotinate hydrobromide
Empirical Formula (Hill Notation):
C8H13NO2 · HBr
CAS Number:
Molecular Weight:
236.11
Beilstein:
3914826
EC Number:
MDL number:
PubChem Substance ID:

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

172-176 °C (lit.)

application(s)

clinical
food and beverages

format

neat

SMILES string

Br[H].COC(=O)C1=CCCN(C)C1

InChI

1S/C8H13NO2.BrH/c1-9-5-3-4-7(6-9)8(10)11-2;/h4H,3,5-6H2,1-2H3;1H

InChI key

AXOJRQLKMVSHHZ-UHFFFAOYSA-N

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General description

Arecoline hydrobromide is an arecoline salt of hydrobromic acid generally used in removing parasites from dog′s intestine. It has a strong parasympathomimetic action.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Arecoline hydrobromide may have been used as working standard in the determination of arecoline concentration from dog plasma using LC–MS/MS.

Legal Information

VETRANAL is a registered trademark of Sigma-Aldrich Chemie GmbH

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Certificate of Origin

Sarah L Withey et al.
The Journal of pharmacology and experimental therapeutics, 366(2), 397-409 (2018-05-23)
Evidence suggests that the α4β2, but not the α7, subtype of the nicotinic acetylcholine receptor (nAChR) plays a key role in mediating the behavioral effects of nicotine and related drugs. However, the importance of other nAChR subtypes remains unclear. The
A Dakkak et al.
Acta tropica, 165, 26-32 (2016-07-21)
This study was undertaken in the Province of Sidi Kacem in northwest Morocco between April 2010 and March 2011. The main objective of the study was to determine the prevalence of Echinococcus granulosus (Eg) infection in owned dogs. This province
Sid Ahmed Labed et al.
Immunity, 48(5), 963-978 (2018-05-17)
Regulated antimicrobial peptide expression in the intestinal epithelium is key to defense against infection and to microbiota homeostasis. Understanding the mechanisms that regulate such expression is necessary for understanding immune homeostasis and inflammatory disease and for developing safe and effective
Yi-Ping Huang et al.
Clinical and experimental pharmacology & physiology, 44(8), 880-887 (2017-04-30)
Activation of peroxisome proliferator-activated receptor alpha (PPARα) has been reported to disrupt tumour metabolism and to promote anticancer activity through interfering with the Warburg effect. This study is to investigate whether Warburg effect-related proteins also could be identified in oral
Osamu Uehara et al.
Oncology letters, 14(1), 1186-1192 (2017-07-12)
Betel quid chewing is implicated in the high prevalence of oral cancer in Southeast Asian countries. One of the major components of betel quid is arecoline. In the present study, in order to characterize the association between chronic arecoline stimulation

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