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Supelco

Bronopol

PESTANAL®, analytical standard

Synonym(s):

2-Bromo-2-nitro-1,3-propanediol, BNPD, BNPK, Bronopol

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About This Item

Linear Formula:
HOCH2C(Br)(NO2)CH2OH
CAS Number:
Molecular Weight:
199.99
Beilstein/REAXYS Number:
1705868
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

130-133 °C (lit.)

application(s)

agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

SMILES string

OCC(Br)(CO)[N+]([O-])=O

InChI

1S/C3H6BrNO4/c4-3(1-6,2-7)5(8)9/h6-7H,1-2H2

Inchi Key

LVDKZNITIUWNER-UHFFFAOYSA-N

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General description

Bronopol is a broad-spectrum antibacterial agent. It is mostly used as a preservative in cosmetic, toiletry etc. It is also used in aerosol formulations.1

Application

Bronopol has been used as reference standard in ultra performance liquid chromatography (UPLC) coupled to inductively coupled plasma mass spectrometry (UPLC-ICP-MS) method for determination of bromine containing preservatives from cosmetic products.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

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Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

4.1B - Flammable solid hazardous materials

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Hyphenation of ultra performance liquid chromatography (UPLC) with inductively coupled plasma mass spectrometry (ICP-MS) for fast analysis of bromine containing preservatives.
Bendahl L et.al.
Journal of Pharmaceutical and Biomedical Analysis, 40(3), 648-652 (2006)
C Gonzalo et al.
Journal of dairy science, 87(11), 3623-3628 (2004-10-16)
A total of 31 individual ovine milk samples, ranging between 30 and 2600 x 10(3) cells/mL, were divided into 8 aliquots/milk with the objective of studying the overall accuracy of 2 rapid somatic cell count (SCC) counters, one based on
Andrew P Shinn et al.
Veterinary parasitology, 186(3-4), 229-236 (2011-12-14)
Pyceze™ (Novartis Animal Vaccines Ltd.) is licensed as a veterinary medicine to treat fungal infections in salmon, trout and their eggs. The active ingredient is bronopol, which due to its broad-spectrum activity has the potential to be an effective treatment
Ahmad Asadinezhad et al.
Colloids and surfaces. B, Biointerfaces, 77(2), 246-256 (2010-03-02)
Medical-grade polyvinyl chloride was surface modified by a multistep physicochemical approach to improve bacterial adhesion prevention properties. This was fulfilled via surface activation by diffuse coplanar surface barrier discharge plasma followed by radical graft copolymerization of acrylic acid through surface-initiated
František Bílek et al.
Colloids and surfaces. B, Biointerfaces, 88(1), 440-447 (2011-08-06)
Low-density polyethylene (LDPE) samples were treated in air plasma discharge, coated by polyallyamine brush thought copolymeric grafting surface-from reaction and deposited four common antibacterial agents (benzalkonium chloride, bronopol, chlorhexidine and triclosan) to gain material with active antibacterial properties. Surface characteristics

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