32539

Nodularin solution

10 μg/mL in methanol, analytical standard

• Synonym(s): Cyclo[(2S,3S,4E,6E,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-4,6-decadienoyl-D-γ-glutamyl-(2Z)-2-(methylamino)-2-butenoyl-(3S)-3-methyl-Dβ-aspartyl-L-arginyl), Nodularin-R solution
• Empirical Formula (Hill Notation): C₄₁H₆₀N₈O₁₀
• CAS Number: 118399-22-7
• Molecular Weight: 824.96
• NACRES: NA.24
• PubChem Substance ID: 329754016
• UNSPSC Code: 85151701
• EC Number: 200-659-6
• MDL number: MFCD16659855

Properties

• InChI key: IXBQSRWSVIBXNC-HSKGSTCASA-N
• InChI: 1S/C41H60N8O10/c1-8-31-38(54)48-34(40(57)58)26(5)36(52)46-29(15-12-20-44-41(42)43)37(53)45-28(25(4)35(51)47-30(39(55)56)18-19-33(50)49(31)6)17-16-23(2)21-24(3)32(59-7)22-27-13-10-9-11-14-27/h8-11,13-14,16-17,21,24-26,28-30,32,34H,12,15,18-20,22H2,1-7H3,(H,45,53)(H,46,52)(H,47,51)(H,48,54)(H,55,56)(H,57,58)(H4,42,43,44)/b17-16+,23-21+,31-8-/t24-,25-,26-,28-,29-,30+,32-,34+/m0/s1
• SMILES string: CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(C)\C=C\[C@@H]2NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](C)[C@@H](NC(=O)\C(=C\C)N(C)C(=O)CC[C@@H](NC(=O)[C@H]2C)C(O)=O)C(O)=O
• grade: analytical standard
• shelf life: limited shelf life, expiry date on the label
• concentration: 10 μg/mL in methanol
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): cleaning products; cosmetics; food and beverages; personal care
• format: single component solution
• storage temp.: −20°C
• Quality Level: 100

Description

General description

Nodularins belong to the class of hepatotoxic cyclic pentapeptides and have their structures resembling to that of microcystins. They are produced by Nodularia spumigena cyanobacterium.[1]

Application

Nodularin may be used as an analytical reference standard for the determination of the analyte in:

• Surface and drinking waters by on-line solid phase extraction (SPE) and ultra high pressure liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS).[2]
• Sediments and pore waters by accelerated solvent extraction (ASE) and HPLC-MS/MS.[3]

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Safety Information

• pictograms: GHS02,GHS06,GHS08
• signalword: Danger
• hcodes: H225,H301 + H311 + H331,H370
• pcodes: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• target_organs: Eyes
• Storage Class: 3 - Flammable liquids
• wgk: WGK 1
• flash_point_f: 51.8 °F
• flash_point_c: 11 °C
• ppe: Eyeshields, Faceshields, Gloves