32904

Supelco

Cefalonium hydrate

VETRANAL®, analytical standard

Empirical Formula (Hill Notation):
C20H18N4O5S2 · xH2O
Molecular Weight:
458.51 (anhydrous basis)
EC Number:
MDL number:
PubChem Substance ID:
Pricing and availability is not currently available.

Quality Level

grade

analytical standard

product line

VETRANAL®

form

neat

CofA

certificate is enclosed in each package

shelf life

limited shelf life, expiry date on the label

application(s)

HPLC: suitable
gas chromatography (GC): suitable

Featured Industry

Clinical
Forensics and Toxicology
Pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

O.NC(=O)c1cc[n+](CC2=C(N3[C@H](SC2)[C@H](NC(=O)Cc4cccs4)C3=O)C([O-])=O)cc1

InChI

1S/C20H18N4O5S2.H2O/c21-17(26)11-3-5-23(6-4-11)9-12-10-31-19-15(18(27)24(19)16(12)20(28)29)22-14(25)8-13-2-1-7-30-13;/h1-7,15,19H,8-10H2,(H3-,21,22,25,26,28,29);1H2/t15-,19-;/m1./s1

InChI key

GVIOXNHDFXYYMP-AEFICSSHSA-N

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General description

Cefalonium is a cephalosporin antibiotic which belongs to the β-lactam class, used in both human and veterinary medicine. Its mode of action involves inhibiting of enzymes involved in the biosynthesis of cell wall peptidoglycan resulting in the lysis of bacteria.
Chemical structure: ß-lactam

Application

Commission Regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Cefalonium hydrate may be used for the determination of cefalonium in bovine muscle by liquid chromatography coupled to tandem mass spectrometry.

Legal Information

VETRANAL is a registered trademark of Sigma-Aldrich Chemie GmbH

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
J E Hillerton et al.
Journal of dairy science, 82(4), 704-711 (1999-04-23)
The use of antibiotic therapy to treat and prevent udder infections of cows during the dry period is a key component of mastitis control in many countries. At the same time, the general public is becoming increasingly aware of potential...
R W Shephard et al.
Australian veterinary journal, 82(10), 624-629 (2005-05-13)
To investigate and compare the therapeutic efficacy of dry cow agents containing either cephalonium or cloxacillin within Australian dairy herds. A treatment-control trial. Milk from infected quarters of cows with high somatic cell counts in milk on eight Australian dairy...
[Effect of and length of protection offered by Cepravin Dry Cow in the prevention of summer-mastitis (author's transl)].
J Sol et al.
Tijdschrift voor diergeneeskunde, 107(12), 466-474 (1982-06-15)
A J Bradley et al.
Journal of dairy science, 93(4), 1566-1577 (2010-03-27)
The dry period is a critical time in the lactation cycle, being the optimum time to cure existing intramammary infection (IMI) as well as encompassing the periods of highest susceptibility to new infection. Currently, IMI in the dry period is...
Change in treatment to calving interval for Cepravin Dry Cow.
Andrew Montgomery
The Veterinary record, 155(1), 32-32 (2004-07-22)

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