32972

Supelco

Lactofen

PESTANAL®, analytical standard

Synonym(s):
Ethyl O-5-(2-chloro-α,α,α-trifluoro-p-tolyloxy)-2-nitrobenzoyl-DL-lactate, 2-Ethoxy-1-methyl-2-oxoethyl 5-(2-chloro-4-trifluoromethylphenoxy)-2-nitrobenzoate
Empirical Formula (Hill Notation):
C19H15ClF3NO7
CAS Number:
Molecular Weight:
461.77
MDL number:
PubChem Substance ID:
NACRES:
NA.24
Pricing and availability is not currently available.

Quality Level

grade

analytical standard

product line

PESTANAL®

form

neat

CofA

certificate is enclosed in each package

shelf life

limited shelf life, expiry date on the label

application(s)

HPLC: suitable
gas chromatography (GC): suitable

Featured Industry

Agriculture
Environmental

format

neat

SMILES string

CCOC(=O)C(C)OC(=O)c1cc(Oc2ccc(cc2Cl)C(F)(F)F)ccc1N+(O-)=O

InChI

1S/C19H15ClF3NO7/c1-3-29-17(25)10(2)30-18(26)13-9-12(5-6-15(13)24(27)28)31-16-7-4-11(8-14(16)20)19(21,22)23/h4-10H,3H2,1-2H3

InChI key

CONWAEURSVPLRM-UHFFFAOYSA-N

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Related Categories

General description

Lactofen is a broad-spectrum post-emergent herbicide. It acts by inhibiting protoporphyrinogen oxidase by causing lipid peroxidation of the cell membrane.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Lactofen may be used as an analytical reference standard for the determination of the analyte in:
  • Environmental samples by high performance liquid chromatography (HPLC) coupled to tandem mass spectrometric detector (MS/MS), ultraviolet (UV) detector and circular dichroism (CD) detector.
  • Fruit and wheat flour matrices by on-line turbulent flow chromatography (TFC) combined with LC-MS/MS.
  • Agricultural products using gas chromatography coupled to flame photometric detector (GC-FPD).

Legal Information

PESTANAL is a registered trademark of Sigma-Aldrich International GmbH

Pictograms

Exclamation markEnvironment

Signal Word

Warning

Hazard Statements

Precautionary Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes

Xn,N

Risk Statement

21-51/53

Safety Statement

36/37-61

RIDADR

UN 3077 9 / PGIII

WGK Germany

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Fang Wang et al.
Chemosphere, 213, 443-452 (2018-09-25)
Pesticide residue in agricultural land might led to contamination of fresh waters, creating potential risks to organisms. The environmental behavior of herbicide lactofen may be enantioselective and the metabolites may have high toxic effects in individual or in combination. In...
E G Butler et al.
Toxicology and applied pharmacology, 93(1), 72-80 (1988-03-30)
A technical grade of lactofen (1'[carboethoxy]ethyl 5-[2-chloro-4-[trifluoro-methyl] phenoxy]-2-nitrobenzoate) has been shown to induce liver tumors in mice. To determine a possible mechanism of action, the effect of exposure for 7 weeks to dietary concentrations of 2, 10, 50, and 250...
Jing Zhang et al.
Journal of hazardous materials, 341, 336-345 (2017-08-13)
A bacterial strain Za capable of degrading diphenyl ether herbicide lactofen was isolated and identified as Bacillus sp. This strain could degrade 94.8% of 50mgL
William L Patzoldt et al.
Proceedings of the National Academy of Sciences of the United States of America, 103(33), 12329-12334 (2006-08-09)
Herbicides that act by inhibiting protoporphyrinogen oxidase (PPO) are widely used to control weeds in a variety of crops. The first weed to evolve resistance to PPO-inhibiting herbicides was Amaranthus tuberculatus, a problematic weed in the midwestern United States that...
Bo Liang et al.
Journal of agricultural and food chemistry, 58(17), 9711-9715 (2010-08-18)
The diphenyl ether herbicide lactofen is commonly used to control broadleaf weeds. Once released into the environment, this herbicide is subject to microbial reactions. This study describes the biotransformation of lactofen by Brevundimonas sp. LY-2 isolated from enrichment cultures inoculated...

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