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33034

Sigma-Aldrich

L-Ascorbic acid

puriss. p.a., ACS reagent, reag. ISO, Ph. Eur., 99.7-100.5% (oxidimetric)

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Synonym(s):
L-Threoascorbic acid, Antiscorbutic factor, Vitamin C
Empirical Formula (Hill Notation):
C6H8O6
CAS Number:
Molecular Weight:
176.12
Beilstein:
84272
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

biological source

synthetic

Quality Level

grade

ACS reagent
puriss. p.a.

Agency

Ph. Eur.
USP/NF
reag. ISO

Assay

99.7-100.5% (oxidimetric)

form

solid

optical activity

[α]20/D +20.5 to +21.5°, c = 10% in H2O

technique(s)

IR spectroscopy: suitable

impurities

related substances, in accordance (HPLC)
≤0.001% heavy metals (by ICP-OES)

ign. residue

≤0.05% (as SO4)

loss

≤0.1% loss on drying, 105 °C

pH

2.1-2.6 (20 °C, 5%)

mp

190-194 °C (dec.)

solubility

water: soluble 176 g/L at 20 °C

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤20 mg/kg

cation traces

As: ≤1 mg/kg
Cu: ≤5 mg/kg
Fe: ≤2 mg/kg
Pb: ≤5 mg/kg
Zn: ≤10 mg/kg

suitability

complies for appearance of solution
passes test for identity (IR)

application(s)

cell analysis

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Gene Information

human ... SLC23A2(9962)

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This Item
25556479543795210
L-Ascorbic acid puriss. p.a., ACS reagent, reag. ISO, Ph. Eur., 99.7-100.5% (oxidimetric)

Sigma-Aldrich

33034

L-Ascorbic acid

L-Ascorbic acid ACS reagent, ≥99%

Sigma-Aldrich

255564

L-Ascorbic acid

L-Ascorbic acid anhydrous, free-flowing, Redi-Dri™, ACS reagent, ≥99%

Sigma-Aldrich

795437

L-Ascorbic acid

L-Ascorbic acid puriss. p.a., ≥99.0% (RT)

Sigma-Aldrich

95210

L-Ascorbic acid

grade

ACS reagent, puriss. p.a.

grade

ACS reagent

grade

ACS reagent, anhydrous

grade

-

assay

99.7-100.5% (oxidimetric)

assay

≥99%

assay

≥99%

assay

≥99.0% (RT)

form

solid

form

chunks, crystalline powder, crystals, granular

form

powder

form

powder or crystals (possibly with chunks)

technique(s)

IR spectroscopy: suitable

technique(s)

HPLC: suitable, cell culture | mammalian: suitable

technique(s)

-

technique(s)

-

mp

190-194 °C (dec.)

mp

190-194 °C (dec.)

mp

190-194 °C (dec.)

mp

190-194 °C (dec.)

General description

L-Ascorbic acid or vitamin C is a water-soluble vitamin found in various foodstuffs. Benefits of vitamin C may include protection against immune system deficiencies, cardiovascular disease, hyperpigmentation, skin protection, anti-aging, iron absorption, and red blood cell production. It is also useful in the biosynthesis of collagen, L-carnitine, and neurotransmitters.

Application

L-Ascorbic acid has been used as an analytical interfering substance in glycated albumin (GA) enzymatic assay.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Vitamin C: One compound, several uses. Advances for delivery, efficiency and stability
Testa R, et al.
Nanomedicine: Nanotechnology, Biology, and Medicine, 1(2), 162-171 (2016)
A family of mammalian NaI[plus]I-dependent L-ascorbic acid transporters.
Tsukaguchi H, et al.
Nature, 673(1), 70-75 (1999)
Total phenols, ascorbic acid, β-carotene and lycopene in Portuguese wild edible mushrooms and their antioxidant activities.
Barros L, et al.
Food Chemistry, 103(2), 413-419 (2007)
T R Tickner et al.
Clinica chimica acta; international journal of clinical chemistry, 85(2), 125-129 (1978-04-17)
A new colorimetric method for the assay of biliverdin in biological fluids is described. The method, based upon the reaction of biliverdin with barbituric acid, offers improved sensitivity and selectivity when compared to direct spectrophotometric measurements. Using this method biliverdinaemia
Vitamin C: One compound, several uses. Advances for delivery, efficiency and stability
Carita AC, et al.
Nanomedicine: Nanotechnology, Biology, and Medicine, 31(2), 102117-102117 (2019)

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