MilliporeSigma
All Photos(3)

Documents

340855

Sigma-Aldrich

Glutaraldehyde solution

50 wt. % in H2O

Sign Into View Organizational & Contract Pricing

Synonym(s):
Glutaric dialdehyde solution, Pentane-1,5-dial
Linear Formula:
OHC(CH2)3CHO
CAS Number:
Molecular Weight:
100.12
Beilstein/REAXYS Number:
605390
MDL number:
PubChem Substance ID:
NACRES:
NA.21

vapor density

1.05 (vs air)

Quality Level

vapor pressure

15 mmHg ( 20 °C)

form

liquid

concentration

50 wt. % in H2O

technique(s)

electron microscopy: suitable
immunoblotting: suitable
immunohistochemistry: suitable

color

colorless

refractive index

n20/D 1.42

mp

-21  °C ((-6 °F))

solubility

water: soluble

density

1.106 g/mL at 25 °C

suitability

suitable for microfluidics/nanofluidics

application(s)

cell analysis
genomic analysis
life science and biopharma
sample preparation

SMILES string

[H]C(CCCC([H])=O)=O

InChI

1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2

InChI key

SXRSQZLOMIGNAQ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
G7776G64033802
Glutaraldehyde solution 50 wt. % in H2O

340855

Glutaraldehyde solution

Glutaraldehyde solution Grade I, 70% in H2O, specially purified for use as an electron microscopy fixative or other sophisticated use

G7776

Glutaraldehyde solution

Glutaraldehyde solution 50% in H2O, suitable for photographic applications

G6403

Glutaraldehyde solution

Glutaraldehyde solution for in vitro diagnostic use

3802

Glutaraldehyde solution

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

500

form

liquid

form

liquid

form

liquid

form

solution

density

1.106 g/mL at 25 °C

density

-

density

-

density

-

refractive index

n20/D 1.42

refractive index

-

refractive index

-

refractive index

-

mp

-21  °C ((-6 °F))

mp

-

mp

-21  °C ((-6 °F))

mp

-

General description

Glutaraldehyde (Glutaric dialdehyde, Pentane-1,5-dial) is an aliphatic dialdehyde that can be employed as an effective biochemical reagent for various purposes such as a protein crosslinker, enzyme immobilization in microscopy, histochemistry, and cytochemistry. It serves as an amine-reactive homobifunctional crosslinker and a cell fixative before SDS-PAGE, staining, or electron microscopy, making it suitable for a wide range of morphological studies.

Glutaraldehyde is capable of efficiently crosslinking amine and hydrazine derivatives to proteins and other amine-containing polymers. Notably, in certain reactions, biotin hydrazides have been directly coupled to nucleic acids using glutaraldehyde, presenting a potential utility in conjugating fluorescent hydrazides and hydroxylamines to DNA. In histology studies, Glutaraldehyde is also employed to preserve tissue sections and prepare them for closer examination.

Application

Cross-linking agent for gelatin, poly(vinyl alcohol), and polyheptapeptides.
Glutaraldehyde may be used in the following studies:
  • To compose the fixative solution (Glutaraldehyde + Paraformaldehyde + NaPO4) for use in high-resolution light microscopy and electron microscopy studies.
  • To study the conjugation of goat anti-horseradish peroxidase with alkaline phosphatase by a reported method.
  • To compose the primary fixative, which is employed to protect the deterioration of cytoplasmic features of yeast cells during permanganate fixation.

Features and Benefits

  • Versatile and adaptable for wide variety of research applications
  • Ready-made solution reduces the need for preparation time

Other Notes

For additional information on our range of Biochemicals, please complete this form.
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

supp_hazards

Storage Class

6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 2

1 of 2

Biomimetics, 1, 219-219 (1992)
Minutes Int. Symp. Microencapsulation, 9th, 191-191 (1993)
Polymer Journal (1993)
Chem. Abstr., 121, 52250t-52250t (1994)
Preservation of fine structures in yeast by fixation in a dimethyl sulfoxide-acrolein-glutaraldehyde solution.
D W Schwab et al.
Stain technology, 45(4), 143-147 (1970-07-01)

Related Content

Three-dimensional (3D) printing of biological tissue is rapidly becoming an integral part of tissue engineering.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service