402907

Propionic acid

ACS reagent grade, ≥99.5%, liquid

• Synonym(s): Acid C₃, Propanoic acid, Propanyl acid
• Linear Formula: CH₃CH₂COOH
• CAS Number: 79-09-4
• Molecular Weight: 74.08
• Beilstein/REAXYS Number: 506071
• EC Number: 201-176-3
• MDL number: MFCD00002756
• UNSPSC Code: 12352100
• eCl@ss: 39021305
• PubChem Substance ID: 24865136
• NACRES: NA.21

Properties

• Product Name: Propionic acid, ACS reagent, ≥99.5%
• grade: ACS reagent
• Quality Level: 200
• vapor density: 2.55 (vs air)
• vapor pressure: 2.4 mmHg ( 20 °C)
• assay: ≥99.5%
• form: liquid
• autoignition temp.: 955 °F
• expl. lim.: 12.1 %
• analyte chemical class(es): amino acids
• impurities: ≤0.002% Carbonyl compounds; ≤0.10% Readily oxidizable substances (as HCOOH); ≤0.15% water
• evapn. residue: ≤0.01%
• color: APHA: ≤20
• refractive index: n20/D 1.386 (lit.)
• bp: 141 °C (lit.)
• mp: −24-−23 °C (lit.)
• solubility: H₂O: soluble
• density: 0.993 g/mL at 25 °C (lit.)
• cation traces: heavy metals (as Pb): ≤0.001%
• functional group: carboxylic acid
• SMILES string: CCC(O)=O
• InChI: 1S/C3H6O2/c1-2-3(4)5/h2H2,1H3,(H,4,5)
• InChI key: XBDQKXXYIPTUBI-UHFFFAOYSA-N

Description

General description

Propionic acid (PA) also known as propanoic acid is a short chain fatty acid mainly used as food preservative.[1] It is one of the main metabolic end product formed during the fermentation of undigested food in the colon by the microbiota.[2] Its manufacture by glycerol/glucose co-fermentation using Propionibacterium acidipropionici has been reported.[3] Crystal structure study reveals that PA crystals are monoclinic with space group P2₁/c.[4]

Propionic acid (PA) is a naturally occurring carboxylic acid, which in its pure state exists as a colorless corrosive liquid with an unpleasant odor. It is miscible in water. Industrially it is produced by hydrocarboxylation of ethylene in presence nickel carbonyl as a catalyst.[5] PA has been found to reduce food intake, lower the fatty acids content in plasma and liver, might improve tissue insulin sensitivity and exerts immunosuppressive actions.[6] Propionic acid is an excellent raw material as it is stable, cheap and safe and can even be used as a food additive.[7]

Application

Propionic acid may be used to alter limestone in order to increase its ability of CO₂ uptake.[8]

Safety Information

• pictograms: GHS02,GHS05,GHS07
• signalword: Danger
• hcodes: H226,H314,H335
• pcodes: P210 - P233 - P240 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 1
• flash_point_f: 129.2 °F - closed cup
• flash_point_c: 54 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter