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42754

Ginsenoside Rk1

analytical standard

Synonym(s):

(3β, 12β)-12-Hydroxydammara-20,24-dien-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside

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Pack SizeSKUAvailabilityPrice
5 mg
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$775.00

About This Item

Empirical Formula (Hill Notation):
C42H70O12
CAS Number:
Molecular Weight:
767.00
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

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grade

analytical standard

Quality Level

assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

format

neat

storage temp.

2-8°C

SMILES string

CC1(C)[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)CC[C@@]4(C)[C@@]1([H])CC[C@]5(C)[C@]4([H])C[C@@H](O)[C@@]6([H])[C@@]5(C)CC[C@@]6(C(CCC=C(C)C)=C)[H]

InChI

1S/C42H70O12/c1-21(2)10-9-11-22(3)23-12-16-42(8)30(23)24(45)18-28-40(6)15-14-29(39(4,5)27(40)13-17-41(28,42)7)53-38-36(34(49)32(47)26(20-44)52-38)54-37-35(50)33(48)31(46)25(19-43)51-37/h10,23-38,43-50H,3,9,11-20H2,1-2,4-8H3/t23-,24-,25-,26-,27+,28-,29+,30

InChI key

KWDWBAISZWOAHD-MHOSXIPRSA-N

General description

Ginsenoside Rk1 is the major bioactive component isolated from heat-processed Panax ginseng Meyer (ginseng) plants. It is a monomeric compound that has been reported to exhibit anti-inflammatory, anti-allergic, and anti-tumor properties and is utilized for the treatment of cancer and diabetes mellitus.

Application

Ginsenoside Rk1 may be used as an analytical reference standard for the determination of the analyte in Panax ginseng preparations and Chinese medicine formula Sheng-Mai San (SMS) and rat plasma samples (post administration of SMS) by chromatography techniques.

Other Notes

This compound is commonly found in plants of the genus: panax

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This Item
PHR2200PHL8574068317
grade

analytical standard

grade

certified reference material, pharmaceutical secondary standard

grade

primary reference standard

grade

analytical standard

format

neat

format

neat

format

-

format

neat

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

-

Quality Level

100

Quality Level

300

Quality Level

-

Quality Level

100

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

limited shelf life, expiry date on the label

assay

≥95.0% (HPLC)

assay

-

assay

≥85.0% (HPLC)

assay

≥90% (HPLC)


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Anti-tumor activity of the ginsenoside Rk1 in human hepatocellular carcinoma cells through inhibition of telomerase activity and induction of apoptosis
Kim YJ, et al.
Biological & Pharmaceutical Bulletin, 31(5), 826-830 (2008)
Simultaneous determination of 30 ginsenosides in Panax ginseng preparations using ultra performance liquid chromatography
Park HW, et al.
Journal of ginseng research, 37(4), 457-457 (2013)
Ginsenoside Rk1 suppresses pro-inflammatory responses in lipopolysaccharide-stimulated RAW264. 7 cells by inhibiting the Jak2/Stat3 pathway
Qian YU, et al.
Chinese Journal of Natural Medicines, 15(10), 751-757 (2017)



Global Trade Item Number

SKUGTIN
42754-5MG04061832104607

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