432202

Sigma-Aldrich

Rhodamine 110 chloride

Dye content ≥75 %

Empirical Formula (Hill Notation):
C20H14N2O3 · HCl
CAS Number:
Molecular Weight:
366.80
Beilstein/REAXYS Number:
4631860
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.47

Quality Level

form

powder or crystals

composition

Dye content, ≥75%

application(s)

hematology: suitable
histology: suitable

mp

>300 °C (lit.)

λmax

496 nm

Featured Industry

Diagnostic Assay Manufacturing

storage temp.

room temp

SMILES string

Cl.Nc1ccc2c(OC3=CC(=N)C=CC3=C2c4ccccc4C(O)=O)c1

InChI

1S/C20H14N2O3.ClH/c21-11-5-7-15-17(9-11)25-18-10-12(22)6-8-16(18)19(15)13-3-1-2-4-14(13)20(23)24;/h1-10,21H,22H2,(H,23,24);1H

InChI key

JNGRENQDBKMCCR-UHFFFAOYSA-N

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General description

Rhodamine 110 chloride (R110) is a laser grade dye.

Application

Rhodamine 110 chloride has been used for the synthesis of the rhodamine 110 octadecyl ester (R110C18).

Packaging

1 g in glass bottle
250 mg in glass bottle

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Aya Shibata et al.
Bioorganic & medicinal chemistry letters, 18(7), 2246-2249 (2008-03-25)
We have developed a new fluorescent probe for biological thiol. The probe was synthesized by the modification of the 2,4-dinitrobenzenesulfonyl group with rhodamine 110. The selective detection of thiol species such as cysteine or glutathione was achieved in biological conditions....
Michelle M Martinez et al.
Analytical and bioanalytical chemistry, 396(3), 1177-1185 (2009-11-26)
Early detection of apoptotic cells via caspase activity is demonstrated with fast response time. Fluorescence correlation spectroscopy (FCS) is used to identify the presence of a cleaved fluorogenic probe based on the fluorescence of rhodamine 110 in Jurkat cells. FCS...
Melissa M Yatzeck et al.
Bioorganic & medicinal chemistry letters, 18(22), 5864-5866 (2008-07-04)
A derivative of rhodamine 110 has been designed and assessed as a probe for cytochrome P450 activity. This probe is the first to utilize a 'trimethyl lock' that is triggered by cleavage of an ether bond. In vitro, fluorescence was...
Jaime G Mayoral et al.
Applied biochemistry and biotechnology, 160(1), 1-8 (2009-01-28)
A novel end-point fluorimetric procedure based on the use of rhodamine-110-labeled specific substrate was developed to determine trypsin activities in biological samples. We evaluated the ability of trichloroacetic acid and acetic acid to stop the enzymatic reaction without hindering the...
Sambashiva Banala et al.
ACS chemical biology, 7(2), 289-293 (2011-10-27)
A caged rhodamine 110 derivative for the specific labeling of SNAP-tag fusion proteins is introduced. The caged rhodamine 110 derivative permits the labeling of cell surface proteins in living cells and of intracellular proteins in fixed cells. The probe requires...

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