43530

Reserpine Standard for LC-MS

analytical standard, for LC-MS

• Synonym(s): Reserpine, (3β, 16β, 17α, 18β, 20α)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester
• Empirical Formula (Hill Notation): C₃₃H₄₀N₂O₉
• CAS Number: 50-55-5
• Molecular Weight: 608.68
• Beilstein/REAXYS Number: 102014
• MDL number: MFCD00005091
• UNSPSC Code: 41121800
• PubChem Substance ID: 329756346
• NACRES: NB.21

Properties

• grade: analytical standard
• Quality Level: 100
• shelf life: limited shelf life, expiry date on the label
• concentration: 5 mg/L in water: isopropyl alcohol (1:1)
• technique(s): LC/MS: suitable
• mp: ~265 °C (dec.)
• suitability: corresponds for mass spectrometry
• storage temp.: 2-8°C
• SMILES string: CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5cc(OC)ccc45)[C@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)c6cc(OC)c(OC)c(OC)c6
• InChI: 1S/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/t18-,22+,24-,27-,28+,31+/m1/s1
• Inchi Key: QEVHRUUCFGRFIF-MDEJGZGSSA-N

Description

General description

Reserpine is a 36 carbon indole alkaloid mostly used as a tranquilizing agent in medicine. It is mostly used as drug for hypertension.[1]

Application

It was used as mass recalibration standard in coupling capillary electrophoresis with electrospray ionization time-of-flight mass spectrometry (CE-TOFMS) to overcome the problem of decreasing the sensitivity during the detection of metabolome differential display.[2]

Biochem/physiol Actions

Inhibits vesicular uptake of catecholamines and serotonin.

Safety Information

• pictograms: GHS02,GHS07
• signalword: Danger
• hcodes: H225,H319,H336
• pcodes: P210 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• target_organs: Central nervous system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 1
• flash_point_f: 71.6 °F - closed cup
• flash_point_c: 22.0 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter