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437581

Sigma-Aldrich

Chloroform

ACS reagent, ≥99.8%, contains 0.5-1.0% ethanol as stabilizer

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Synonym(s):
Methylidyne trichloride, Trichloromethane
Empirical Formula (Hill Notation):
CHCl3
CAS Number:
Molecular Weight:
119.38
Beilstein:
1731042
MDL number:
PubChem Substance ID:

grade

ACS reagent

Quality Level

vapor density

4.1 (vs air)

vapor pressure

160 mmHg ( 20 °C)

Assay

≥99.8%

form

liquid

contains

0.5-1.0% ethanol as stabilizer

packaging

PVC-coated bottle of 4x4 L

evapn. residue

≤0.001%

color

APHA: ≤10

refractive index

n20/D 1.445 (lit.)

bp

60.5-61.5 °C (lit.)
60.5-61.5 °C

mp

−63 °C (lit.)

density

1.492 g/mL at 25 °C (lit.)

cation traces

Pb: ≤0.05 ppm

SMILES string

ClC(Cl)Cl

InChI

1S/CHCl3/c2-1(3)4/h1H

InChI key

HEDRZPFGACZZDS-UHFFFAOYSA-N

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1 of 4

This Item
480150319988372978
Chloroform ACS reagent, ≥99.8%, contains 0.5-1.0% ethanol as stabilizer

Sigma-Aldrich

437581

Chloroform

-
Chloroform ACS reagent, ≥99.8%, contains amylenes as stabilizer

Sigma-Aldrich

480150

Chloroform

-
Chloroform contains ethanol as stabilizer, ACS reagent, ≥99.8%

Sigma-Aldrich

319988

Chloroform

Essential Grade
Chloroform anhydrous, contains amylenes as stabilizer, ≥99%

Sigma-Aldrich

372978

Chloroform

-
vapor density

4.1 (vs air)

vapor density

4.1 (vs air)

vapor density

4.1 (vs air)

vapor density

4.1 (vs air)

vapor pressure

160 mmHg ( 20 °C)

vapor pressure

160 mmHg ( 20 °C)

vapor pressure

160 mmHg ( 20 °C)

vapor pressure

160 mmHg ( 20 °C)

assay

≥99.8%

assay

≥99.8%

assay

≥99.8%

assay

≥99%

form

liquid

form

liquid

form

liquid

form

liquid

refractive index

n20/D 1.445 (lit.)

refractive index

n20/D 1.445 (lit.)

refractive index

n20/D 1.445 (lit.)

refractive index

n20/D 1.445 (lit.)

General description

Chloroform is a colorless, volatile chlorinated organic solvent whose vapors have narcotic effect. It is susceptible to degradation with time which can be suppressed by adding ethanol as a stabilizer. Since ethanol is added in higher concentration it leads to increase in polarity which may have a potential influence on some of the applications.

Application

Chloroform may be used in the following processes:
  • Synthesis of colloidal hydrophobic CdSe core nanocrystals (quantum dots).
  • Preparing phospholipid solutions.
  • As a solvent in the photolysis reaction of ruthenium complexes.
  • Solvent for recrystallization.
  • As a reference compound to detect the presence of chloroform in tobacco smokes.
  • As an extractant in solvent extraction process.

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash


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The affinity of two antimicrobial peptides derived from bovine milk proteins for model lipid membranes.
Barzyk W, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 343(1), 104-110 (2009)
Kinetics and Mechanism of the Photooxidation of Bis (bipyridine) dichlororuthenium (II) and the Photoreduction of Bis (bipyridine) dichlororuthenium (III) in Chloroform.
Sathiyabalan S and Hoggard PE.
Inorganic Chemistry, 34(18), 4562-4571 (1995)
Systematic studies on the breakdown of p,p'-DDT in tobacco smokes. Presence of methyl chloride, dichloromethane, and chloroform in tobacco smokes.
Chopra NM and Sherman LR.
Analytical Chemistry, 44(6), 1036-1038 (1972)
Engineering of ultra-small diagnostic nanoprobes through oriented conjugation of single-domain antibodies and quantum dots.
Sukhanova A, et al.
Protocol Exchange (2012)
Eagleson M.
Concise Encyclopedia Chemistry, 216-216 (1994)

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