439223

Dichloromethane

suitable for HPLC, ≥99.9%, contains 40-150 ppm amylene as stabilizer

• Synonym(s): Methylene chloride
• Empirical Formula (Hill Notation): CH₂Cl₂
• CAS Number: 75-09-2
• Molecular Weight: 84.93
• Beilstein: 1730800
• EC Number: 200-838-9
• MDL number: MFCD00000881
• PubChem Substance ID: 24867491
• NACRES: NA.21

Properties

• vapor density: 2.9 (vs air)
• Quality Level: 100
• vapor pressure: 24.45 psi ( 55 °C); 6.83 psi ( 20 °C)
• Assay: ≥99.9%
• form: liquid
• autoignition temp.: 1223 °F
• contains: 40-150 ppm amylene as stabilizer
• expl. lim.: 22 %
• technique(s): HPLC: suitable
• impurities: Free halogens, passes test; ≤0.0003 meq/g Titr. acid; ≤0.02% water
• evapn. residue: <0.0003%
• color: APHA: ≤10; clear
• refractive index: n20/D 1.424 (lit.)
• bp: 39.8-40 °C (lit.)
• mp: −95 °C (lit.)
• density: 1.325 g/mL at 25 °C (lit.)
• λ: H₂O reference
• UV absorption: λ: 235 nm A_max: 1.00; λ: 240 nm A_max: 0.20; λ: 250 nm A_max: 0.05; λ: 260 nm A_max: 0.02; λ: 340-400 nm A_max: 0.01
• suitability: passes test for HPLC
• SMILES string: ClCCl
• InChI: 1S/CH2Cl2/c2-1-3/h1H2
• InChI key: YMWUJEATGCHHMB-UHFFFAOYSA-N

Description

General description

Dichloromethane (DCM) is a chlorinated organic solvent with a wide range of industrial applications. It has C_2v symmetry, low boiling point, high density and is immiscible in water. Degradation of DCM by various methods has been reported. Ultrasonic absorption studies of liquid DCM shows strong relaxation effect. A study reports the dielectric characteristics of DCM over a wide frequency range. DCM is susceptible to degradation with time, which can be suppressed by adding amylene as a stabilizer.

Application

Dichloromethane (Methylene chloride) may be used in the following processes:

• To compose ultrasonic baths for cleaning and protection of aluminum coating over atactic-PMMA (poly(methyl methacrylate)) for dielectric studies.
• Preparation of AMBF₃ (ammoniomethyltrifluoroborate)-conjugated biomolecules.
• Sample preparation for GC-MS (Gas Chromatography-Mass Spectrometry) analysis.
• Preparation of ammonium acetate solvent mixture in combination with isopropanol, acetonitrile and water for mass spectral analysis of neutral lipids.
• Quantification of glutathione (GSH) and glutathione disulfide (GSSG) in biological samples by HPLC and spectrophotometry.
• As an extractant for 2,2-dithioethyl-4-(2′-pyridyl)-4-butyro-γ-lactone.

Meets ACS specifications

Preparation Note

Product filtered through a 0.2 μm filter

Safety Information

• Pictograms: GHS07,GHS08
• Signal Word: Warning
• Hazard Statements: H315 - H319 - H336 - H351
• Precautionary Statements: P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Central nervous system
• Storage Class Code: 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 2
• Flash Point(F): does not flash
• Flash Point(C): does not flash
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves