443468

Sigma-Aldrich

2-Butanone

ACS reagent, ≥99.0%

Synonym(s):
Ethyl methyl ketone, MEK, Methyl ethyl ketone
Linear Formula:
C2H5COCH3
CAS Number:
Molecular Weight:
72.11
Beilstein/REAXYS Number:
741880
EC Number:
MDL number:

grade

ACS reagent

vapor density

2.49 (vs air)

vapor pressure

71 mmHg ( 20 °C)

assay

≥99.0%

autoignition temp.

960 °F

expl. lim.

10.1 %

impurities

≤0.0005 meq/g Titr. acid
≤0.20% water

evapn. residue

≤0.0025%

color

APHA: ≤15

refractive index

n20/D 1.379 (lit.)

bp

80 °C (lit.)

mp

−87 °C (lit.)

density

0.805 g/mL at 25 °C (lit.)

SMILES string

CC(CC)=O

InChI

1S/C4H8O/c1-3-4(2)5/h3H2,1-2H3

InChI key

ZWEHNKRNPOVVGH-UHFFFAOYSA-N

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General description

2-Butanone (Methyl ethyl ketone, MEK), an aliphatic ketone, is considered as aprotic and protophilic solvent. The solvent composition plays an important role in the rate of liquid-phase catalytic hydrogenation of MEK to 2-butanol. The rate constant for the reaction of hydroxyl radicals with MEK has been determined and expressed in Arrhenius form as ΚC2H5COCH3+OH = 6.35*1013 exp(-2270/T) cm3mol-1s-1.

Application

2-Butanone may be used as an oxidizing agent for the conversion of primary alcohols to the corresponding aldehydes via Oppenauer oxidation in the presence of an iridium complex.

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Statements

Target Organs

Central nervous system

Supp Hazards

EUH066

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

UN1193 - class 3 - PG 2 - Ethyl methyl ketone

WGK Germany

WGK 1

Flash Point(F)

26.6 °F - closed cup

Flash Point(C)

-3 °C - closed cup

Densities and viscosities of binary liquid mixtures of 2-butanone with branched alcohols at (293.15 to 313.15)K.
Lomte SB, et al.
Journal of Chemical and Engineering Data, 54(1), 127-130 (2008)
High-Temperature Measurements of the Reactions of OH with a Series of Ketones: Acetone, 2-Butanone, 3-Pentanone, and 2-Pentanone.
Lam KY, et al.
The Journal of Physical Chemistry A, 116(23), 5549-5559 (2012)
Solvent effects in the hydrogenation of 2-butanone.
Akpa BS, et al.
J. Catal., 289, 30-41 (2012)
Iridium-catalyzed Oppenauer oxidations of primary alcohols using acetone or 2-butanone as oxidant.
Suzuki T, et al.
The Journal of Organic Chemistry, 68(4), 1601-1602 (2003)
Shane Avison et al.
Journal of agricultural and food chemistry, 63(28), 6313-6318 (2015-06-23)
A new methodology is presented to measure water-air partition coefficients (Henry's constants) of volatiles, using APCI-MS. Significant advantages over other Henry's constant determination methods include the short measurement and sample preparation time and the possibility for simultaneous measurement of multiple...

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