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44925

DL-Homocysteine

analytical standard

Synonym(s):

2-Amino-4-mercaptobutyric acid

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25 MG

$90.40

$90.40

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About This Item

Linear Formula:
HSCH2CH2CH(NH2)COOH
CAS Number:
454-29-5
Molecular Weight:
135.18
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
329756565
EC Number:
207-222-9
Beilstein/REAXYS Number:
1721683
MDL number:
MFCD00004898

Key Documents

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InChI key

FFFHZYDWPBMWHY-UHFFFAOYSA-N

InChI

1S/C4H9NO2S/c5-3(1-2-8)4(6)7/h3,8H,1-2,5H2,(H,6,7)

SMILES string

NC(CCS)C(O)=O

grade

analytical standard

assay

≥95% (T)

optical activity

[α]/D 0±1°, c = 1 in H2O

shelf life

limited shelf life, expiry date on the label

analyte chemical class(es)

amino acids, peptides, proteins

technique(s)

HPLC: suitable

color

white to off-white

mp

232-233 °C (lit.)

application(s)

food and beverages

format

neat

storage temp.

−20°C

Quality Level

100

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This Item
7376753721PHR1241
DL-Homocysteine analytical standard

Supelco

44925

DL-Homocysteine

L-Histidine certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Supelco

73767

L-Histidine

DL-Norvaline analytical standard

Supelco

53721

DL-Norvaline

L-Methionine Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1241

L-Methionine

format

neat

format

neat

format

neat

format

neat

technique(s)

HPLC: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

grade

analytical standard

grade

certified reference material, TraceCERT®

grade

analytical standard

grade

certified reference material, pharmaceutical secondary standard

assay

≥95% (T)

assay

-

assay

≥98.5% (HPLC), 98.5-101.5% (NT)

assay

-

optical activity

[α]/D 0±1°, c = 1 in H2O

optical activity

-

optical activity

[α]25/D 0.00±0.10°, c = 2 in 5 M HCl

optical activity

-

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

limited shelf life, expiry date on the label

shelf life

-

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
DL-Homocysteine may be used as an analytical reference standard for the quantification of homocysteine in biological samples using different chromatography techniques.

Biochem/physiol Actions

Increased plasma homocysteine is a risk factor for coronary heart disease and carcinogenesis; may be a marker for tumor cell growth.

Analysis Note

identification (LS-MS): identity conforms

Disclaimer

store under argon

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP2079
BCCL3998
BCCJ5130
BCCG7235
BCCG4457

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Rapid measurement of total plasma homocysteine by HPLC
Frick B, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 331(1-2), 19-23 (2003)
Ghulam Mohammad et al.
International journal of molecular sciences, 21(5) (2020-03-11)
High homocysteine is routinely observed in diabetic patients, and this non-protein amino acid is considered as an independent risk factor for diabetic retinopathy. Homocysteine biosynthesis from methionine forms S-adenosyl methionine (SAM), which is a major methyl donor critical in DNA
Pre-column derivatization high-performance liquid chromatographic method for determination of cysteine, cysteinyl-glycine, homocysteine and glutathione in plasma and cell extracts
Katrusiak.EA, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 758(2), 207-212 (2001)
James Ampadu et al.
International journal of cardiology, 178, 12-23 (2014-12-03)
It has been estimated that 5.1million Americans suffer from heart failure. Cognitive impairment has been described as a consequence of heart failure in numerous studies spanning the last three decades. This systematic review helps differentiate "cognitive impairment" into mild cognitive
Yifan Huang et al.
International journal of molecular sciences, 15(4), 6298-6313 (2014-04-17)
Maternal nutrition may influence metabolic profiles in offspring. We aimed to investigate the effect of maternal folic acid supplement on glucose metabolism in mouse offspring fed a high-fat diet (HFD). Sixty C57BL/6 female mice were randomly assigned into three dietary
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