Inactivation of rat liver cytochrome P-450 by the suicide substrates parathion and chloramphenicol.
J Halpert et al.
Drug metabolism reviews, 12(2), 239-259 (1981-01-01)
Steven B Bird et al.
Toxicology, 247(2-3), 88-92 (2008-04-02)
Organophosphorus (OP) pesticides poison more than 3,000,000 people every year in the developing world, mostly through intentional self-poisoning. Advances in medical therapy for OP poisoning have lagged, and current treatment is not highly effective with mortality of up to 40%...
Meha Jaiswal et al.
Environmental science and pollution research international, 19(6), 2055-2062 (2012-01-05)
Removal of malathion from agricultural runoff was studied using novel copper-coated chitosan nanocomposite (CuCH)-a biopolymeric waste obtained from marine industry. Synthesis and characterization of the adsorbent using different spectral techniques like Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy, energy-dispersive...
Courtney Dunn et al.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 19(5), 504-509 (2012-05-19)
Therapies exist for acute organophosphate (OP) exposure but mortality rates remain high (10% to 20%). Currently, treatment focuses on reversing the resultant cholinergic excess effects through the use of atropine. Intralipid fat emulsion (IFE) has been used to treat lipophilic...
Abdul Shafeeuulla Khan et al.
Journal of molecular graphics & modelling, 34, 10-17 (2012-02-07)
The extreme toxicity of organophosphorus nerve agents and pesticides mandates to employ models or simulants in place of the actual compounds in the laboratory. The importance of simulants is known, however, their efficacy for direct comparison with the toxic organophosphorus...