46589

Supelco

Oxacillin sodium salt monohydrate

VETRANAL®, analytical standard

Linear Formula:
C19H18N3O5SNa · H2O
CAS Number:
Molecular Weight:
441.43
Beilstein/REAXYS Number:
4287093
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24
Pricing and availability is not currently available.

Quality Level

grade

analytical standard

Agency/Method

EPA 1694

product line

VETRANAL®

form

neat

shelf life

limited shelf life, expiry date on the label

application(s)

HPLC: suitable
gas chromatography (GC): suitable

Featured Industry

Clinical
Environmental
Forensics and Toxicology
Pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[Na+].[H]O[H].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)c3c(C)onc3-c4ccccc4)C([O-])=O

InChI

1S/C19H19N3O5S.Na.H2O/c1-9-11(12(21-27-9)10-7-5-4-6-8-10)15(23)20-13-16(24)22-14(18(25)26)19(2,3)28-17(13)22;;/h4-8,13-14,17H,1-3H3,(H,20,23)(H,25,26);;1H2/q;+1;/p-1/t13-,14+,17-;;/m1../s1

InChI key

ZVIYWUUZWWBNMB-VICXVTCVSA-M

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General description

Oxacillin is a bactericidal agent, which can be used for the treatment of infections due to penicillinase-producing staphylococci. Its mode of action involves inhibition of bacterial cell wall synthesis and thus affects bacterial penicillin-binding proteins.
Chemical structure: ß-lactam

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Oxacillin sodium salt monohydrate has been used as a reference standard in the determination of the analyte in milk samples by receptor-binding assay test.

Legal Information

VETRANAL is a registered trademark of Sigma-Aldrich Chemie GmbH

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
CRC Desk Reference of Clinical Pharmacology (1997)
Detection of antibiotics in sheep milk by receptor-binding assays.
Beltran CM, et al.
International dairy journal, 34(2), 184-189 (2014)
Bintao Cui et al.
Journal of clinical microbiology, 51(1), 9-14 (2012-10-12)
Coagulase-negative staphylococci have been identified as major causes of late-onset neonatal bacteremia in neonatal intensive care units. Sixty isolates of Staphylococcus capitis obtained from blood cultures of neonates between 2000 and 2005 were examined in this study. Biochemical analysis confirmed...
Kinga Wieczorek et al.
Foodborne pathogens and disease, 9(8), 681-685 (2012-07-26)
Four hundred seventeen retail beef meat samples purchased in the eastern part of Poland during October 2009 to January 2011 were tested for the presence of Listeria monocytogenes. It was found that 81 (19.4%) of them were positive for this...
Xin-Ming Liu et al.
Pharmaceutical research, 29(11), 3169-3179 (2012-06-27)
To develop novel biomineral-binding liposomes (BBL) for the prevention of orthopedic implant associated osteomyelitis. A biomineral-binding lipid, alendronate-tri(ethyleneglycol)-cholesterol conjugate (ALN-TEG-Chol), was synthesized through Cu(I)-catalyzed Huisgen 1,3-dipolar cycloaddition (a versatile click reaction). Mixing with other excipients, the new lipid was used...

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