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50862

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Super-DHB

suitable for matrix substance for MALDI-MS, ≥99.0%

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CAS Number:
NACRES:
NA.21

Quality Level

Assay

≥99.0% (sum of DHB and 2-hydroxy-5-methoxybenzoic acid, HPLC)
≥99.0%

analyte functional class(es)

polymers

analyte chemical class(es)

glycans, peptides, proteins

technique(s)

MALDI-MS: suitable

solubility

methanol: 1%, clear

cation traces

Ca: ≤5 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤5 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

suitability

suitable for matrix substance for MALDI-MS

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This Item
D0426179728142174
Super-DHB suitable for matrix substance for MALDI-MS, ≥99.0%

Supelco

50862

Super-DHB

analyte functional class(es)

polymers

analyte functional class(es)

-

analyte functional class(es)

-

analyte functional class(es)

-

analyte chemical class(es)

glycans, peptides, proteins

analyte chemical class(es)

-

analyte chemical class(es)

-

analyte chemical class(es)

-

technique(s)

MALDI-MS: suitable

technique(s)

-

technique(s)

-

technique(s)

-

solubility

methanol: 1%, clear

solubility

water: 1 tablet/5 mL

solubility

-

solubility

-

cation traces

Ca: ≤5 mg/kg

cation traces

-

cation traces

-

cation traces

-

General description

The “super-DHB” matrix consists of a 9:1 (w/w) mixture of 2,5-DHB and 2-hydroxy-5-methoxybenzoic acid, respectively, since this ratio was found to be the most effective. The beneficial effect of the 2-hydroxy- 5-methoxybenzoic acid additive is attributed to a disorder in the 2,5-DHB crystal lattice resulting in enhanced ion desorption (i.e. ‘softer′ desorption) and reduced internal energy, which in turn results in reduced metastable fragmentation. An increase in sensitivity of up to 2 to 3-fold has been reported for a standard dextran mixture with concomitant enhanced resolution attributed to reduced metastable ion formation. The super-DHB matrix has also been reported to generate enhanced signals from tryptic glycopeptides. The use of super-DHB matrix is reported to reduce the presence of matrix background ions and result in glycan signals exhibiting better signal to noise ratios and higher resolution in the mass spectrum.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Analysis Note

9:1 mixture of DHB and 2-hydroxy-5-methoxybenzoic acid

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Description
Pricing

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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