51834

Supelco

Sodium 1-heptanesulfonate solution

suitable for ion pair chromatography, concentrate, LiChropur, ampule

Synonym(s):
1-Heptanesulfonic acid sodium salt
Linear Formula:
CH3(CH2)5CH2SO3Na
CAS Number:
Molecular Weight:
202.25
Beilstein/REAXYS Number:
3731762
MDL number:
PubChem Substance ID:
Pricing and availability is not currently available.

Quality Level

description

anionic

quality

LiChropur
ampule

packaging

ampule of 25 mL

application(s)

HPLC: suitable
ion pair chromatography: suitable

λ

in concentrate

UV absorption

λ: 210 nm Amax: 0.07
λ: 220 nm Amax: 0.04
λ: 230 nm Amax: 0.03
λ: 260 nm Amax: 0.01
λ: 500 nm Amax: 0.01

suitability

corresponds to standard for RP gradient test
corresponds to standard for filter test

SMILES string

[Na].CCCCCCCS(O)(=O)=O

InChI

1S/C7H16O3S.Na/c1-2-3-4-5-6-7-11(8,9)10;/h2-7H2,1H3,(H,8,9,10);/q;+1/p-1

InChI key

REFMEZARFCPESH-UHFFFAOYSA-M

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General description

Concentrate for 6x1 L ready-to-use solution. Dilute contents of one ampule (~0.3 M) to 1 L with HPLC grade water to obtain a 0.005 M eluent solution.

Application

Sodium 1-heptanesulfonate may be used as an ion-pairing reagent for the determination of ethambutol in pharmaceutical dosage forms by ion-pair reversed phase liquid chromatography with UV detection.

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Determination of ethambutol by ion-pair reversed phase liquid chromatography with UV detection.
Jiang Z, et al.
Analytica Chimica Acta, 456(2), 189- 192 (2002)
Takeshi Oshizaka et al.
International journal of pharmaceutics, 475(1-2), 292-297 (2014-08-27)
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European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 88(2), 510-517 (2014-07-06)
Severe intoxications with organophosphates require the immediate administration of atropine in combination with acetyl cholinesterase (AChE) reactivators such as HI-6. Although this therapy regimen enables the treatment of peripheral symptoms, the blood-brain barrier (BBB) restricts the access of the hydrophilic...
Jie Ma et al.
Pharmacology, 93(5-6), 220-224 (2014-07-12)
It is significant for patients with traumatic brain injury (TBI) to receive prehospital emergency treatment as early as possible to reduce mortality. Therefore, a new prefilled multi-drug injector was developed to improve the treatment of TBI. Here, we studied the...

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