MilliporeSigma
All Photos(2)

52341

Supelco

Salicylic acid

certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Synonym(s):
2-Hydroxybenzoic acid
Linear Formula:
2-(HO)C6H4CO2H
CAS Number:
Molecular Weight:
138.12
Beilstein:
774890
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material
TraceCERT®

Quality Level

vapor density

4.8 (vs air)

vapor pressure

1 mmHg ( 114 °C)

product line

TraceCERT®

manufacturer/tradename

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

211 °C (lit.)

mp

158-161 °C (lit.)

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical

format

neat

SMILES string

OC(=O)c1ccccc1O

InChI

1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)

InChI key

YGSDEFSMJLZEOE-UHFFFAOYSA-N

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1 of 4

This Item
W398500PHR1013S-019
Salicylic acid certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Supelco

52341

Salicylic acid

Salicylic acid ≥99%, FG

Sigma-Aldrich

W398500

Salicylic acid

Salicylic acid Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1013

Salicylic acid

Salicylic acid 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

Supelco

S-019

Salicylic acid

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

GC/MS: suitable, gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical

application(s)

flavors and fragrances

application(s)

pharmaceutical (small molecule)

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

format

-

format

neat

format

single component solution

Quality Level

300

Quality Level

400

Quality Level

300

Quality Level

300

vapor density

4.8 (vs air)

vapor density

4.8 (vs air)

vapor density

4.8 (vs air)

vapor density

4.8 (vs air)

General description

Salicylic acid is a commonly used keratolytic, which finds applications in breaking down keratin in the skin. It is also used to get rid of warts on the skin and this depends on the depth and size of the warts.
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.
This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Legal Information

TraceCERT is a registered trademark of Sigma-Aldrich Co. LLC

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

314.6 °F - closed cup

Flash Point(C)

157 °C - closed cup


Certificates of Analysis (COA)

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Applied Pharmacology (2011)
S G Owen et al.
British journal of clinical pharmacology, 38(4), 349-355 (1994-10-01)
1. Five rheumatoid patients with a knee joint effusion participated in the study. An aqueous solution (0.1 to 0.2 ml) containing paracetamol, salicylate, diclofenac and [125I]-albumin was injected into a given joint to yield target concentrations of approximately 20 micrograms
Zheng Qing Fu et al.
Annual review of plant biology, 64, 839-863 (2013-02-05)
Systemic acquired resistance (SAR) is an induced immune mechanism in plants. Unlike vertebrate adaptive immunity, SAR is broad spectrum, with no specificity to the initial infection. An avirulent pathogen causing local programmed cell death can induce SAR through generation of
S Zaugg et al.
Journal of chromatography. B, Biomedical sciences and applications, 752(1), 17-31 (2001-03-20)
Acetylsalicylic acid (Aspirin) is rapidly metabolized to salicylic acid (salicylate) and other compounds, including gentisic acid and salicyluric acid. Monitoring of salicylate and its metabolites is of toxicological, pharmacological and biomedical interest. Three capillary electrophoresis (CE) methods featuring alkaline aqueous
Dorothea Ellinger et al.
Plant physiology, 161(3), 1433-1444 (2013-01-22)
A common response by plants to fungal attack is deposition of callose, a (1,3)-β-glucan polymer, in the form of cell wall thickenings called papillae, at site of wall penetration. While it has been generally believed that the papillae provide a

Protocols

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