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56197

Supelco

3-Hydroxypicolinic acid

matrix substance for MALDI-MS, ≥99.0% (HPLC)

Synonym(s):
3-HPA, 3-Hydroxypyridine-2-carboxylic acid
Empirical Formula (Hill Notation):
C6H5NO3
CAS Number:
Molecular Weight:
139.11
Beilstein:
118954
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

grade

matrix substance for MALDI-MS

Quality Level

Assay

≥99.0% (HPLC)

form

solid

analyte chemical class(es)

oligonucleotides, oligosaccharides

technique(s)

MALDI-MS: suitable

mp

213-218 °C (lit.)

cation traces

Ba: ≤5 mg/kg
Ca: ≤50 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤20 mg/kg
K: ≤20 mg/kg
Mg: ≤50 mg/kg
Mn: ≤5 mg/kg
Na: ≤100 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤50 mg/kg

SMILES string

OC(=O)c1ncccc1O

InChI

1S/C6H5NO3/c8-4-2-1-3-7-5(4)6(9)10/h1-3,8H,(H,9,10)

InChI key

BRARRAHGNDUELT-UHFFFAOYSA-N

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3-Hydroxypicolinic acid matrix substance for MALDI-MS, ≥99.0% (HPLC)

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3-Hydroxypicolinic acid

2,5-Dihydroxybenzoic acid matrix substance for MALDI-MS, ≥99.5% (HPLC), Ultra pure

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2,5-Dihydroxybenzoic acid

2,5-Dihydroxybenzoic acid matrix substance for MALDI-MS, >99.0% (HPLC)

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2,5-Dihydroxybenzoic acid

6-Hydroxynicotinic acid Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR2470

6-Hydroxynicotinic acid

form

solid

form

-

form

powder

form

powder

mp

213-218 °C (lit.)

mp

203-207 °C, 204-208 °C (lit.)

mp

200-207 °C, 204-208 °C (lit.)

mp

>300 °C (lit.)

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

-

grade

matrix substance for MALDI-MS

grade

matrix substance for MALDI-MS

grade

matrix substance for MALDI-MS

grade

certified reference material, pharmaceutical secondary standard

analyte chemical class(es)

oligonucleotides, oligosaccharides

analyte chemical class(es)

glycans, lipids, organic molecules, peptides, proteins

analyte chemical class(es)

glycans, lipids, organic molecules, peptides, proteins

analyte chemical class(es)

-

Application

3-Hydroxypicolinic acid (3-HPA) is a matrix material used in matrix-assisted laser desorption/ionization (MALDI) based mass spectroscopy (MS) for the analysis of large biomolecules and quantification of oligonucleotides.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

3-Hydroxypicolinic acid has been used in the study conducted to isolate and characterize bacteria degrading-quinoline in subsurface sediments.

related product

Product No.
Description
Pricing

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Customers Also Viewed

Slide 1 of 3

1 of 3

Gas-phase diagnostics and LIF-imaging of 3-hydroxypicolinic acid MALDI-matrix plumes
Puretzky AA and Geohegan DB
Chemical Physics Letters, 286(5-6), 425-432 (1998)
K Tang et al.
Nucleic acids research, 23(16), 3126-3131 (1995-08-25)
Matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) mass spectrometry was used to analyze short DNA duplex probes with one strand immobilized on solid supports (straptavidin-coated magnetic beads or controlled pore glass beads). Only the non-immobilized strand could be detected. Partial denaturation
P Juhasz et al.
Carbohydrate research, 270(2), 131-147 (1995-04-30)
Molecular weights of heparin-derived oligosaccharides ranging from disaccharides to hexadecasaccharides have been determined by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. While these compounds ionize poorly or not at all when used as such, a strong signal can be obtained
Isolation and characterization of quinoline-degrading bacteria from subsurface sediments.
Applied and Environmental Microbiology, 55 (4), 1029-1032 (1989)
Accurate characterization of carcinogenic DNA adducts using MALDI tandem time-of-flight mass spectrometry.
Barnes C A and Chiu N H
International Journal of Mass Spectrometry, 279(2-3), 170-175 (2009)

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