574724

Acetonitrile solution

suitable for HPLC, contains 0.05 % (v/v) trifluoroacetic acid

• Synonym(s): ACN, Cyanomethane, Ethyl nitrile, Methyl cyanide
• Linear Formula: CH₃CN
• CAS Number: 75-05-8
• Molecular Weight: 41.05
• Beilstein/REAXYS Number: 4124158
• EC Number: 200-835-2
• MDL number: MFCD00001878
• UNSPSC Code: 12190000
• PubChem Substance ID: 57651625
• NACRES: NA.03
• technique(s): HPLC: suitable
• bp: 81-82 °C (lit.)
• vapor pressure: 72.8 mmHg

Properties

• Product Name: Acetonitrile solution, contains 0.05 % (v/v) trifluoroacetic acid
• vapor density: 1.41 (vs air)
• Quality Level: 100
• vapor pressure: 72.8 mmHg
• form: liquid
• contains: 0.05 % (v/v) trifluoroacetic acid
• expl. lim.: 8 % (lit.)
• technique(s): HPLC: suitable
• bp: 81-82 °C (lit.)
• mp: -48 °C (lit.)
• density: 0.782 g/mL at 25 °C
• format: mixture
• SMILES string: CC#N
• InChI: 1S/C2H3N/c1-2-3/h1H3
• InChI key: WEVYAHXRMPXWCK-UHFFFAOYSA-N

Description

General description

The product is an acetonitrile solution containing 0.05%v/v trifluoroacetic acid. This pre-blended mobile phase solvent is of high purity that reduces time-consuming preparation and prevents instrument downtime because of impure mobile phases. Trifluoroacetic acid/acetonitrile mobile phase system is generally employed for peptide separation. Acetonitrile (MeCN), an organic solvent[1] has low viscosity, high elution strength and is UV transparent at low wavelength.[2] Trifluoroacetic acid (TFA) is commonly used as a mobile phase additive. It is a UV transparent, volatile acid that forms hydrophobic negatively charged trifluoroacetate ion.[3]

Preparation Note

Product filtered through a 0.2 μm filter

Safety Information

• pictograms: GHS02,GHS07
• signalword: Danger
• hcodes: H225,H302 + H312 + H332,H319
• pcodes: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 2
• flash_point_f: 42.8 °F - closed cup
• flash_point_c: 6 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter