574732

Sigma-Aldrich

Acetonitrile solution

contains 0.1 % (v/v) trifluoroacetic acid, suitable for HPLC

Linear Formula:
CH3CN
CAS Number:
Molecular Weight:
41.05
Beilstein/REAXYS Number:
4124158
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.03

Quality Level

vapor density

1.41 (vs air)

vapor pressure

72.8 mmHg

form

liquid

contains

0.1 % (v/v) trifluoroacetic acid

expl. lim.

8 %

application(s)

HPLC: suitable

bp

81-82 °C

mp

-48 °C

density

0.782 g/mL at 25 °C

Featured Industry

Food and Beverages

SMILES string

CC#N

InChI

1S/C2H3N/c1-2-3/h1H3

InChI key

WEVYAHXRMPXWCK-UHFFFAOYSA-N

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General description

The product is an acetonitrile solution containing 0.1%v/v trifluoroacetic acid. This pre-blended mobile phase solvent is of high purity that reduces time-consuming preparation and prevents instrument downtime because of impure mobile phases. Trifluoroacetic acid/acetonitrile mobile phase system is generally employed for peptide separation. Acetonitrile (MeCN), an organic solvent has low viscosity, high elution strength and is UV transparent at low wavelength. Trifluoroacetic acid (TFA) is commonly used as a mobile phase additive. It is a volatile acid that forms hydrophobic negatively charged trifluoroacetate ion.

Packaging

20 L in Nowpak™
200 L in Pure-Pac™ 1
4, 4×4 L in glass bottle
18 L in VerSA-Flow™

Preparation Note

Product filtered through a 0.2 μm filter

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Pictograms

FlameExclamation mark

Signal Word

Danger

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

UN 1648 3 / PGII

WGK Germany

WGK 2

Flash Point(F)

42.8 °F - closed cup

Flash Point(C)

6 °C - closed cup

Certificate of Analysis

Certificate of Origin

Optimum concentration of trifluoroacetic acid for reversed-phase liquid chromatography of peptides revisited.
Chen Y, et al.
Journal of Chromatography A, 1043(1), 9-18 (2004)
Eagleson M.
Concise Encyclopedia Chemistry, 6-6 (1994)
Acetonitrile, the polarity chameleon.
Zarzycki PK, et al.
Analytical and Bioanalytical Chemistry, 397(3), 905-908 (2010)
Maria de la Paz Celorio-Mancera et al.
Insect biochemistry and molecular biology, 61, 34-45 (2015-05-03)
More than half of the proteome from mandibular glands in caterpillars is represented by chemosensory proteins. Based on sequence similarity, these proteins are putative transporters of ligands to gustatory receptors in sensory organs of insects. We sought to determine whether...
Divya Subramonian et al.
Journal of proteome research, 13(9), 3905-3918 (2014-07-30)
SUMOylation is an essential posttranslational modification and regulates many cellular processes. Dysregulation of SUMOylation plays a critical role in metastasis, yet how its perturbation affects this lethal process of cancer is not well understood. We found that SUMO-2/3 modification is...

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