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574732

Sigma-Aldrich

Acetonitrile solution

contains 0.1 % (v/v) trifluoroacetic acid, suitable for HPLC

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Linear Formula:
CH3CN
CAS Number:
75-05-8
Molecular Weight:
41.05
Beilstein:
4124158
EC Number:
200-835-2
MDL number:
MFCD00001878
PubChem Substance ID:
57651626
NACRES:
NA.03

vapor density

1.41 (vs air)

Quality Level

100

vapor pressure

72.8 mmHg

form

liquid

contains

0.1 % (v/v) trifluoroacetic acid

expl. lim.

8 %

technique(s)

HPLC: suitable

bp

81-82 °C

mp

-48 °C

density

0.782 g/mL at 25 °C

application(s)

food and beverages

format

mixture

SMILES string

CC#N

InChI

1S/C2H3N/c1-2-3/h1H3

InChI key

WEVYAHXRMPXWCK-UHFFFAOYSA-N

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This Item
574724576956685461
Acetonitrile solution contains 0.1 % (v/v) trifluoroacetic acid, suitable for HPLC

Sigma-Aldrich

574732

Acetonitrile solution

Acetonitrile solution contains 0.05 % (v/v) trifluoroacetic acid

Sigma-Aldrich

574724

Acetonitrile solution

Acetonitrile solution contains 0.1 % (v/v) formic acid, suitable for HPLC

Sigma-Aldrich

576956

Acetonitrile solution

Acetonitrile solution contains 10.0% acetone, 0.05% formic acid, 40.0% 2-propanol

Sigma-Aldrich

685461

Acetonitrile solution

vapor pressure

72.8 mmHg

vapor pressure

72.8 mmHg

vapor pressure

72.8 mmHg

vapor pressure

72.8 mmHg

form

liquid

form

liquid

form

liquid

form

liquid

expl. lim.

8 %

expl. lim.

8 % (lit.)

expl. lim.

8 %

expl. lim.

8 %

technique(s)

HPLC: suitable

technique(s)

HPLC: suitable

technique(s)

HPLC: suitable

technique(s)

HPLC: suitable

bp

81-82 °C

bp

81-82 °C (lit.)

bp

81-82 °C

bp

81-82 °C

General description

The product is an acetonitrile solution containing 0.1%v/v trifluoroacetic acid. This pre-blended mobile phase solvent is of high purity that reduces time-consuming preparation and prevents instrument downtime because of impure mobile phases. Trifluoroacetic acid/acetonitrile mobile phase system is generally employed for peptide separation. Acetonitrile (MeCN), an organic solvent has low viscosity, high elution strength and is UV transparent at low wavelength. Trifluoroacetic acid (TFA) is commonly used as a mobile phase additive. It is a volatile acid that forms hydrophobic negatively charged trifluoroacetate ion.

Packaging

View returnable container options.

Preparation Note

Product filtered through a 0.2 μm filter

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Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

42.8 °F - closed cup

Flash Point(C)

6 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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25G
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Optimum concentration of trifluoroacetic acid for reversed-phase liquid chromatography of peptides revisited.
Chen Y, et al.
Journal of Chromatography A, 1043(1), 9-18 (2004)
Acetonitrile, the polarity chameleon.
Zarzycki PK, et al.
Analytical and Bioanalytical Chemistry, 397(3), 905-908 (2010)
Eagleson M.
Concise Encyclopedia Chemistry, 6-6 (1994)
Maria de la Paz Celorio-Mancera et al.
Insect biochemistry and molecular biology, 61, 34-45 (2015-05-03)
More than half of the proteome from mandibular glands in caterpillars is represented by chemosensory proteins. Based on sequence similarity, these proteins are putative transporters of ligands to gustatory receptors in sensory organs of insects. We sought to determine whether
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Journal of proteome research, 13(9), 3905-3918 (2014-07-30)
SUMOylation is an essential posttranslational modification and regulates many cellular processes. Dysregulation of SUMOylation plays a critical role in metastasis, yet how its perturbation affects this lethal process of cancer is not well understood. We found that SUMO-2/3 modification is
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