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648531

Sigma-Aldrich

N,N-Dimethylformamide

suitable for HPLC, ≥99.9%

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Synonym(s):
DMF, NSC 5356
Linear Formula:
HCON(CH3)2
CAS Number:
Molecular Weight:
73.09
Beilstein:
605365
EC Number:
MDL number:
PubChem Substance ID:

vapor density

2.5 (vs air)

Quality Level

vapor pressure

2.7 mmHg ( 20 °C)

Assay

≥99.9%

form

liquid

autoignition temp.

833 °F

expl. lim.

15.2 %

technique(s)

HPLC: suitable

impurities

≤0.030% water

evapn. residue

≤0.0005%

refractive index

n20/D 1.430 (lit.)

bp

153 °C (lit.)

mp

−61 °C (lit.)

density

0.944 g/mL (lit.)

absorption

0.010 at 340 nm
0.010 at 400 nm
0.05 at 310 nm
0.10 at 295 nm
0.30 at 275 nm
1.00 at 270 nm

application(s)

food and beverages

SMILES string

[H]C(=O)N(C)C

InChI

1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3

InChI key

ZMXDDKWLCZADIW-UHFFFAOYSA-N

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1 of 4

This Item
494488319937270547
N,N-Dimethylformamide suitable for HPLC, ≥99.9%

Sigma-Aldrich

648531

N,N-Dimethylformamide

-
N,N-Dimethylformamide biotech. grade, ≥99.9%

Sigma-Aldrich

494488

N,N-Dimethylformamide

-
N,N-Dimethylformamide ACS reagent, ≥99.8%

Sigma-Aldrich

319937

N,N-Dimethylformamide

Essential Grade
N,N-Dimethylformamide suitable for HPLC, ≥99.9%

Sigma-Aldrich

270547

N,N-Dimethylformamide

-
vapor pressure

2.7 mmHg ( 20 °C)

vapor pressure

2.7 mmHg ( 20 °C)

vapor pressure

2.7 mmHg ( 20 °C)

vapor pressure

2.7 mmHg ( 20 °C)

assay

≥99.9%

assay

≥99.9%

assay

≥99.8%

assay

≥99.9%

form

liquid

form

liquid

form

liquid

form

liquid

autoignition temp.

833 °F

autoignition temp.

833 °F

autoignition temp.

833 °F

autoignition temp.

833 °F

expl. lim.

15.2 %

expl. lim.

15.2 %

expl. lim.

15.2 %

expl. lim.

15.2 %

General description

N,N-Dimethylformamide (DMF) is the commonly employed solvent for chemical reactions. DMF is a useful solvent employed for the isolation of chlorophyll from plant tissues. It is widely employed reagent in organic synthesis. It plays multiple roles in various reactions such as solvent, dehydrating agent, reducing agent as well as catalyst. It is a multipurpose building block for the synthesis of compounds containing O, -CO, -NMe2, -CONMe2, -Me, -CHO as functional groups. Dielectric relaxation experiments on DMF have been conducted between 238.15K and 338.15K. The thermophysical properties of the molecular interactions between DMF and the ionic liquids, ammonium salts and imidazolium salts have been studied. The characteristics of solute-solvent interactions between ammonium nitrate and DMF have been investigated.

Application

Solvent for many hydrophobic organic compounds.

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Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 1B

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

135.5 °F - closed cup

Flash Point(C)

57.5 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Measurements and molecular interactions for N,N-dimethylformamide with ionic liquid mixed solvents.
Attri P, et al.
The Journal of Physical Chemistry B, 114(18), 6126-6133 (2010)
Volumetric properties of ammonium nitrate in N,N-dimethylformamide.
Vranes M, et al.
The Journal of Chemical Thermodynamics, 54, 245-249 (2012)
Synthesis and electrochemical characterization of aPEO-based polymer electrolytes.
Rodrigues LC, et al.
Journal of Solid State Electrochemistry, 16(4), 1623-1629 (2012)
The dynamics of liquid formamide, N-methylformamide, N,N-dimethylformamide, and N,N-dimethylacetamide. A dielectric relaxation study.
Barthel J, et al.
Journal of Molecular Liquids, 98, 51-69 (2002)
W P Inskeep et al.
Plant physiology, 77(2), 483-485 (1985-02-01)
We found inconsistencies in the commonly used data for chlorophyll analysis in 80% acetone. Recently developed extinction coefficients for chlorophyll b in N,N-dimethylformamide (DMF) based on values from 80% acetone are low as a result of these inconsistencies. We determined

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