68790

Drometrizole trisiloxane

analytical standard

• Synonym(s): 2-(2H-Benzotriazol-2-yl)-4-methyl-6-{2-methyl-3-{1,3,3,3-tetramethyl-1-[(trimethylsilyl)oxy]disiloxanyl}propyl}phenol, Silatrizole
• Empirical Formula (Hill Notation): C₂₄H₃₉N₃O₃Si₃
• CAS Number: 155633-54-8
• Molecular Weight: 501.84
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329760825
• MDL number: MFCD22373626
• Beilstein/REAXYS Number: 11343300

Properties

• format: neat
• Quality Level: 100
• InChI: 1S/C24H39N3O3Si3/c1-18-14-20(15-19(2)17-33(9,29-31(3,4)5)30-32(6,7)8)24(28)23(16-18)27-25-21-12-10-11-13-22(21)26-27/h10-14,16,19,28H,15,17H2,1-9H3
• SMILES string: CC(Cc1cc(C)cc(c1O)-n2nc3ccccc3n2)C[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C
• InChI key: HUVYTMDMDZRHBN-UHFFFAOYSA-N
• grade: analytical standard
• assay: ≥98.0% (HPLC)
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): cleaning products; cosmetics; environmental; food and beverages; personal care

Description

General description

Drometrizole trisiloxane (DRT) belongs to the lipophilic benzotriazole derivative class of compounds commonly utilized in sunscreen cosmetics.[1]

Application

DRT may be used as a reference standard for the determination of DRT in:

• Active pharmaceutical ingredients (APIs), formulations and stability samples by reversed phase ultra-high performance liquid chromatography (RP-UPLC) coupled to electrospray ionization-quadrupole time-of-flight tandem mass spectrometry (ESI-QTOF-MS/MS).[1]
• Suncare formulations by high performance liquid chromatography (HPLC) with ultraviolet (UV) detection.[2]
• Cosmetic products by LC-UV.[3]
• Sewage sludge samples by QuEChERS (quick, easy, cheap, effective, rugged, and safe) extraction procedure and gas chromatography combined with MS/MS.[4]

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Safety Information

• hcodes: H413
• pcodes: P273 - P501
• Hazard Classifications: Aquatic Chronic 4
• Storage Class: 10 - Combustible liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable