68909

Supelco

Sennoside A

analytical standard

Empirical Formula (Hill Notation):
C42H38O20
CAS Number:
Molecular Weight:
862.74
Beilstein/REAXYS Number:
5723746
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24
Pricing and availability is not currently available.

grade

analytical standard

Quality Level

assay

≥96.0% (HPLC)

form

neat

CofA

certificate is enclosed in each package

application(s)

HPLC: suitable
gas chromatography (GC): suitable

Featured Industry

Food and Beverages

format

neat

SMILES string

OCC@H1OC@@H(Oc2cccc3C@@H(C@@H4c5cccc(OC@H6OC@H(CO)C@@H(O)C@H(O)C@H6O)c5C(=O)c7c(O)cc(cc47)C(O)=O)c8cc(cc(O)c8C(=O)c23)C(O)=O)C@H(O)C@@H(O)C@@H1O

InChI

1S/C42H38O20/c43-11-23-31(47)35(51)37(53)41(61-23)59-21-5-1-3-15-25(17-7-13(39(55)56)9-19(45)27(17)33(49)29(15)21)26-16-4-2-6-22(60-42-38(54)36(52)32(48)24(12-44)62-42)30(16)34(50)28-18(26)8-14(40(57)58)10-20(28)46/h1-10,23-26,31-32,35-38,41-48,51-54H,11-12H2,(H,55,56)(H,57,58)/t23-,24-,25-,26-,31-,32-,35+,36+,37-,38-,41-,42?/m1/s1

InChI key

IPQVTOJGNYVQEO-GTCVFCFLSA-N

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General description

Sennoside A is a hydroxy anthracene glycoside generally present in the polyherbal formulations that contain Cassia angustifolia leaves, which is used in the treatment of constipation.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Status of sennosides content in various Indian herbal formulations: method standardization by HPTLC
Aktar W, et al.
Bangladesh Journal of Pharmacology, 3, 64-68 (2008)
Osamu Morinaga et al.
Phytochemical analysis : PCA, 20(2), 154-158 (2009-01-15)
Rhubarb, senna and sennoside-containing preparations are currently widely employed as purgatives. The major active components of these medications are sennoside A (SA) and sennoside B (SB). To develop an eastern blotting technique for the specific visualisation and easy determination of...
Yongguo Zhang et al.
Fitoterapia, 83(6), 1014-1022 (2012-06-07)
Berberine, a compound isolated from Chinese Goldthread Rhizome, has been widely used as a non-prescription drug to treat diarrhoea in China. Previous studies have demonstrated multiple pharmacological activities for berberine, including its significant role in antimicrobial activity. However, its effect...
Meng-Ting Wang et al.
European journal of heart failure, 13(11), 1238-1243 (2011-08-02)
Digoxin is an important medication for heart failure (HF) patients and sennosides are widely used to treat constipation. Recently, safety concerns have been raised about a possible interaction between sennosides and digoxin, an issue that has not been studied empirically....
Yuko Mishima et al.
Digestion, 77(3-4), 166-172 (2008-06-26)
Colonoscopy plays an important role in the diagnosis and treatment of gastrointestinal illness in both Western countries and Japan. However, preparative bowel cleansing for colonoscopy is frequently troublesome for elderly and/or constipated patients, since they must drink larger volumes of...

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