MilliporeSigma
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69193

Supelco

Methyl nicotinate

analytical standard

Synonym(s):
Nicotinic acid methyl ester
Empirical Formula (Hill Notation):
C7H7NO2
CAS Number:
Molecular Weight:
137.14
Beilstein:
113951
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

Quality Level

grade

analytical standard

assay

≥98.0% (GC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

color

white to off-white

bp

204 °C (lit.)

mp

39-42 °C
42-44 °C (lit.)

solubility

H2O: 10%, clear to very faintly turbid, colorless

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

format

neat

SMILES string

COC(=O)c1cccnc1

InChI

1S/C7H7NO2/c1-10-7(9)6-3-2-4-8-5-6/h2-5H,1H3

InChI key

YNBADRVTZLEFNH-UHFFFAOYSA-N

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General description

Methyl nicotinate is a volatile product of certain fruits such as carambola, soursop, wild strawberries, etc. It is used for a variety of applications in food products, cosmetics, and medicinal products.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Methyl nicotinate may be used as a test compound to study the percutaneous penetration of methyl nicotinate through human skin in vitro and in vivo using micro-dialysis technique and different analytical techniques.
Methyl nicotinate may be used as an analytical reference standard for the determination of the analyte in biological samples, cosmetics, and pharmaceuticals by various chromatography techniques.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Determination of nicotinic acid and metabolites in urine, cosmetics, and pharmaceuticals by high-performance liquid chromatography with novel electrochemical detection
Wang L-H
Analytical Letters, 49(10), 1467-1479 (2016)
Determination of methyl nicotinate in pharmaceutical creams by high-performance thin-layer chromatography
De Spiegeleer B, et al.
Chromatographia, 20(4), 249-252 (1985)
HPLC-quantification of diethylamine salicylate and methyl nicotinate in ointments
Abounassif MA, et al.
Journal of Liquid Chromatography and Related Technologies, 15(4), 625-636 (1992)
Active Ingredients Used in Cosmetics: Safety Survey
Health protection of consumers (2008)
Microdialysis technique as a method to study the percutaneous penetration of methyl nicotinate through excised human skin, reconstructed epidermis, and human skin in vivo
Boelsma E, et al.
Pharmaceutical Research, 17(2), 141-147 (2000)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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