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69532

Supelco

Artemisinin

analytical standard

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Synonym(s):
Arteannuin, Qinghaosu
Empirical Formula (Hill Notation):
C15H22O5
CAS Number:
Molecular Weight:
282.33
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥98.0% (TLC)

optical activity

[α]/D +75.0±3°, c = 0.5 in methanol

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

156-157 °C (lit.)

application(s)

food and beverages

format

neat

SMILES string

C[C@@H]1CC[C@H]2[C@@H](C)C(=O)O[C@@H]3OC4(C)CC[C@@H]1[C@@]23OO4

InChI

1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1

InChI key

BLUAFEHZUWYNDE-NNWCWBAJSA-N

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This Item
PHL894841042747361593
Artemisinin analytical standard

Supelco

69532

Artemisinin

Artemisinin phyproof® Reference Substance

PHL89484

Artemisinin

Artemisinin United States Pharmacopeia (USP) Reference Standard

USP

1042747

Artemisinin

Artemisinin 98%

Sigma-Aldrich

361593

Artemisinin

format

neat

format

-

format

neat

format

-

assay

≥98.0% (TLC)

assay

≥95.0% (HPLC)

assay

-

assay

98%

optical activity

[α]/D +75.0±3°, c = 0.5 in methanol

optical activity

-

optical activity

-

optical activity

[α]20/D +76°, c = 0.5 in methanol

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

-

technique(s)

HPLC: suitable

technique(s)

-

technique(s)

-

technique(s)

-

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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C Wongsrichanalai et al.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 19(10), 908-916 (2013-09-17)
Following a decade-long scale up of malaria control through vector control interventions, the introduction of rapid diagnostic tests and highly efficacious Artemisinin-based Combination Therapy (ACT) along with other measures, global malaria incidence declined significantly. The recent development of artemisinin resistance
Pamela J Weathers et al.
Journal of ethnopharmacology, 153(3), 732-736 (2014-03-26)
The Chinese have used Artemisia annua as a tea infusion to treat fever for >2000 years. The active component is artemisinin. Previously we showed that when compared to mice fed an equal amount of pure artemisinin, a single oral dose
Benjamin J Visser et al.
Expert opinion on pharmacotherapy, 15(15), 2219-2254 (2014-08-12)
Chemotherapy of malaria has become a rapidly changing field. Less than two decades ago, treatment regimens were increasingly bound to fail due to emerging drug resistance against 4-aminoquinolines and sulfa compounds. By now, artemisinin-based combination therapies (ACTs) constitute the standard
Melissa D Conrad et al.
The Journal of infectious diseases, 210(3), 344-353 (2014-03-13)
Artemisinin-based combination therapies, including artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DP), are recommended to treat uncomplicated falciparum malaria. Sensitivities to components of AL and DP are impacted by polymorphisms in pfmdr1 and pfcrt. We monitored changes in prevalences of polymorphisms in Tororo
Connor O'Brien et al.
Current opinion in infectious diseases, 24(6), 570-577 (2011-10-18)
Artemisinin-based combination therapies (ACTs) have been deployed globally with remarkable success for more than 10 years without having lost their malaria treatment efficacy. However, recent reports from the Thai-Cambodian border reveal evidence of emerging resistance to artemisinins. The latest published

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