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70448

Sigma-Aldrich

2-Naphthol

BioXtra, ≥99.0% (GC)

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Synonym(s):
β-Naphthol, 2-Hydroxynaphthalene
Linear Formula:
C10H7OH
CAS Number:
Molecular Weight:
144.17
Beilstein/REAXYS Number:
742134
EC Number:
MDL number:
PubChem Substance ID:

vapor density

4.97 (vs air)

Quality Level

vapor pressure

10 mmHg ( 145.5 °C)

product line

BioXtra

assay

≥99.0% (GC)

form

solid

bp

285-286 °C (lit.)

mp

120-122 °C (lit.)
121-123 °C

fluorescence

λex 320 nm; λem 410 nm in 0.1 M NaOH

SMILES string

Oc1ccc2ccccc2c1

InChI

1S/C10H8O/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-7,11H

InChI key

JWAZRIHNYRIHIV-UHFFFAOYSA-N

Gene Information

human ... CYP1A2(1544)

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1 of 4

This Item
33420N2780185507
vibrant-m

70448

2-Naphthol

Premium Grade
vibrant-m

33420

1-Naphthol

-
vibrant-m

N2780

1-Naphthol

Premium Grade
vibrant-m

185507

2-Naphthol

-
assay

≥99.0% (GC)

assay

≥99% (GC)

assay

≥99%

assay

99%

form

solid

form

-

form

powder

form

powder or flakes

fluorescence

λex 320 nm; λem 410 nm in 0.1 M NaOH

fluorescence

-

fluorescence

-

fluorescence

-

vapor density

4.97 (vs air)

vapor density

4.5 (120 °C, vs air)

vapor density

4.5 (120 °C, vs air)

vapor density

4.97 (vs air)

vapor pressure

10 mmHg ( 145.5 °C)

vapor pressure

1 mmHg ( 94 °C)

vapor pressure

1 mmHg ( 94 °C)

vapor pressure

10 mmHg ( 145.5 °C)

Other Notes

Substrate for the fluorometric assay of phenol sulfotransferase

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Dam. 1 - Skin Sens. 1

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 2

flash_point_f

307.4 °F - closed cup

flash_point_c

153 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves


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M Arand et al.
Analytical biochemistry, 163(2), 546-551 (1987-06-01)
A new, rapid, and sensitive method for assaying phenol sulfotransferase activity toward 2-naphthol is described. The product 2-naphthyl sulfate is quantitated fluorometrically. Optimal wavelengths for excitation and emission were determined by recording the three-dimensional fluorescence spectra of the substrate and
Glenn Talaska et al.
Toxicology letters, 213(1), 45-48 (2011-05-26)
Urinary bladder cancer is a historical disease of rubber workers often been associated with exposure to aromatic amines such as 2-naphthylamine. While exposure to these compounds has decreased markedly over time, the bladder cancer risk has not decreased in direct
Supriti Sen et al.
The Analyst, 137(17), 3975-3981 (2012-07-13)
An efficient water soluble fluorescent Al(3+) receptor, 1-[[(2-furanylmethyl)imino]methyl]-2-naphthol (1-H) was synthesized and characterized by physico-chemical and spectroscopic tools along with single crystal X-ray crystallography. High selectivity and affinity of 1-H towards Al(3+) in HEPES buffer (DMSO/water: 1/100) of pH 7.4
Erin E Podlesny et al.
Organic letters, 14(6), 1408-1411 (2012-03-01)
The first enantioselective total synthesis of the bisanthraquinone (S)-bisoranjidiol and an unnatural regioisomer has been accomplished. Key features of the synthesis include the asymmetric oxidative biaryl coupling of a hindered 8-substituted 2-naphthol, selective para-quinone formation, and regioselective tandem Diels-Alder/aromatization reactions.
L E King et al.
Environmental science & technology, 48(19), 11637-11645 (2014-08-26)
Hamilton Harbour, Ontario, Canada is one of the most polluted sites on the Great Lakes, and is subject to substantial airborne pollution due to emissions from both heavy industry and intense vehicle traffic. Mutagenic Polycyclic aromatic hydrocarbons (PAHs) are present

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