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Key Documents

70709

Sigma-Aldrich

Hydroxyectoine

≥95% (HPLC)

Synonym(s):

(4S,5S)-5-Hydroxy-2-methyl-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid, THP(A)

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About This Item

Empirical Formula (Hill Notation):
C6H10N2O3
CAS Number:
Molecular Weight:
158.16
MDL number:
UNSPSC Code:
24112111
PubChem Substance ID:
NACRES:
NA.21

Quality Level

assay

≥95% (HPLC)

form

solid

SMILES string

CC1=N[C@@H]([C@@H](O)CN1)C(O)=O

InChI

1S/C6H10N2O3/c1-3-7-2-4(9)5(8-3)6(10)11/h4-5,9H,2H2,1H3,(H,7,8)(H,10,11)/t4-,5-/m0/s1

InChI key

KIIBBJKLKFTNQO-WHFBIAKZSA-N

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Other Notes

Stabilizer for enzymes and biological macromolecules

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Stanislav Obruca et al.
Applied microbiology and biotechnology, 100(3), 1365-1376 (2015-11-23)
Poly(3-hydroxybutyrate) (PHB) is a common carbon- and energy-storage compound simultaneously produced and degraded into its monomer 3-hydroxybutyrate (3HB) by numerous bacteria and Archae in a metabolic pathway called the PHB cycle. We investigated 3HB as a chemical chaperone capable of
Cuixia Guo et al.
Analytical biochemistry, 548, 109-114 (2018-03-03)
The Fe(II)/2-oxoglutarate-dependent dioxygenases (2-OGDs) catalyze the oxidation of substrates ranging from small molecules to large biomolecules with concomitant oxidation of co-substrate (2-oxoglutarate) into succinate. In the present study, we reported a coupled colorimetric assay that can be generally applied to
Marc Benjamin Hahn et al.
Physical chemistry chemical physics : PCCP, 22(13), 6984-6992 (2020-03-20)
Ectoine is a small zwitterionic osmolyte and compatible solute, which does not interfere with cell metabolism even at molar concentrations. Plasmid DNA (pUC19) was irradiated with ultraviolet radiation (UV-C at 266 nm) under quasi physiological conditions (PBS) and in pure
Sara Cantera et al.
Journal of environmental management, 231, 1091-1099 (2019-01-04)
Methane bioconversion into products with a high market value, such as ectoine or hydroxyectoine, can be optimized via isolation of more efficient novel methanotrophic bacteria. The research here presented focused on the enrichment of methanotrophic consortia able to co-produce different
Qi Zhao et al.
Microbial cell factories, 18(1), 184-184 (2019-10-28)
As an attracted compatible solute, 1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid (ectoine) showed great potentials in various field. However, lower productivity and high saline medium seriously hinder its wide applications. The entire ectoine metabolism, including pathways for ectoine synthesis and catabolism, was identified in

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