72210

Sigma-Aldrich

Neutral Red

for microscopy (Bact., Bot., Fl., Hist., Vit.), indicator (pH 6.8-8.0)

Synonym(s):
Toluylene red, 3-Amino-7-dimethylamino-2-methylphenazine hydrochloride, Basic Red 5
Empirical Formula (Hill Notation):
C15H17ClN4
CAS Number:
Molecular Weight:
288.78
Colour Index Number:
50040
Beilstein/REAXYS Number:
3918740
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
MA.02
Pricing and availability is not currently available.

Quality Level

grade

for microscopy (Bact., Bot., Fl., Hist., Vit.)
indicator (pH 6.8-8.0)

form

powder or crystals

application(s)

hematology: suitable
histology: suitable
titration: suitable

pH range

6.8 - 8.0, red to yellow

mp

290 °C (dec.) (lit.)

solubility

water: 0.01 g/10 mL

εmax

≥800 at 535-545 nm

Featured Industry

Diagnostic Assay Manufacturing

storage temp.

room temp

SMILES string

Cl.CN(C)c1ccc2nc3cc(C)c(N)cc3nc2c1

InChI

1S/C15H16N4.ClH/c1-9-6-13-15(8-11(9)16)18-14-7-10(19(2)3)4-5-12(14)17-13;/h4-8H,16H2,1-3H3;1H

InChI key

PGSADBUBUOPOJS-UHFFFAOYSA-N

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General description

Neutral red is a vital dye widely used as a cellular pH indicator and is selective for shifts in pH. It is highly lipophilic in nature. It favours membrane potential dependent fluorescence that attributes to changes in hydrophobicity.

Application

Neutral red has been used to stain mouse mammary glands.
Useful as an indicator for preparing neutral red paper, and as a biological stain.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
John D Landua et al.
Journal of mammary gland biology and neoplasia, 14(4), 411-415 (2009-11-26)
Whole mount preparations of mouse mammary glands are useful for evaluating overall changes in growth and morphology, and are essential for detecting and evaluating focal or regionally-localized phenotypes that would be difficult to detect or analyze using other techniques. We...
Sylvie V M Tesson et al.
Frontiers in microbiology, 9, 2681-2681 (2018-11-30)
Microalgae are common members of the atmospheric microbial assemblages. Diverse airborne microorganisms are known to produce ice nucleation active (INA) compounds, which catalyze cloud and rain formation, and thus alter cloud properties and their own deposition patterns. While the role...
Ayesha Ali et al.
Cell reports, 30(5), 1463-1477 (2020-02-06)
The intact vaginal epithelium is essential for women's reproductive health and provides protection against HIV and sexually transmitted infections. How this epithelium maintains itself remains poorly understood. Here, we used single-cell RNA sequencing (RNA-seq) to define the diverse cell populations...
Cássio do Nascimento et al.
Microscopy research and technique, 76(2), 126-132 (2012-10-31)
The aim of this randomized crossover investigation was to assess the biofilm formation on two titanium and one zirconia substrates in relation to the topography and surface roughness of the materials. Twenty-four discs specimens for each evaluated material (Machined pure...
Robim M Rodrigues et al.
Toxicology in vitro : an international journal published in association with BIBRA, 27(2), 760-767 (2012-12-25)
When in vitro test systems are evaluated for assessment of the toxicity of chemical compounds, particular efforts are made to mimic the in vivo reality as close as possible. Cellular models with appropriate metabolic competence, i.e. with the potency to...

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