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72405

Supelco

1,2-Dimethoxyethane

analytical standard

Synonym(s):
mono-Glyme, Dimethylglycol, Ethylene glycol dimethyl ether, Monoglyme
Linear Formula:
CH3OCH2CH2OCH3
CAS Number:
Molecular Weight:
90.12
Beilstein:
1209237
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

vapor density

3.1 (20 °C, vs air)

vapor pressure

48 mmHg ( 20 °C)

Assay

≥99.7% (GC)

autoignition temp.

396 °F

shelf life

limited shelf life, expiry date on the label

contains

~0.01% 2,6-di-tert-butyl-4-methylphenol as stabilizer

expl. lim.

10.4 %

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.379 (lit.)
n20/D 1.380

bp

85 °C (lit.)

mp

−58 °C (lit.)

density

0.867 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

SMILES string

COCCOC

InChI

1S/C4H10O2/c1-5-3-4-6-2/h3-4H2,1-2H3

InChI key

XTHFKEDIFFGKHM-UHFFFAOYSA-N

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1 of 4

This Item
307432E27408259527
1,2-Dimethoxyethane analytical standard

Supelco

72405

1,2-Dimethoxyethane

1,2-Dimethoxyethane suitable for HPLC, 99.9%, inhibitor-free

Sigma-Aldrich

307432

1,2-Dimethoxyethane

1,2-Dimethoxyethane ReagentPlus®, ≥99%, inhibitor-free

Sigma-Aldrich

E27408

1,2-Dimethoxyethane

1,2-Dimethoxyethane anhydrous, 99.5%, inhibitor-free

Sigma-Aldrich

259527

1,2-Dimethoxyethane

assay

≥99.7% (GC)

assay

99.9%

assay

≥99%

assay

99.5%

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable

technique(s)

-

technique(s)

-

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

application(s)

food and beverages

application(s)

-

application(s)

-

format

neat

format

-

format

-

format

-

General description

1,2-Dimethoxyethane is a water miscible solvent, used as an alternative for the hazardous organic solvents such as dioxane and tetrahydrofuran.

Application

1,2-Dimethoxyethane may be used as a solvent for the separation and determination of neutral sugars as 2,4- dinitrophenyl derivatives using high-performance liquid chromatography.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

recommended

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

41.0 °F - closed cup

Flash Point(C)

5 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

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Analysis of neutral sugars as dinitrophenyl-hydrazones by high-performance liquid chromatography
Karamanos.K.N, et al.
Journal of Chromatography A, 405, 221-228 (1987)
Introduction to Organic Laboratory Techniques: A Small Scale Approach (2005)
Shaokun Tang et al.
Bioresource technology, 129, 667-671 (2013-01-10)
Glymes (i.e. glycol diethers) were explored as alternative benign solvents for enzymatic reactions, specifically the lipase-catalyzed transesterification. Long-chain glymes were found highly compatible with immobilized Candida antarctica lipase B (iCALB), leading to higher enzyme activities and stabilities than t-butanol and
Andrew Martins et al.
Organic letters, 12(22), 5186-5188 (2010-10-19)
A palladium-catalyzed crossed biaryl coupling/reduction sequence enables the formation of meta-substituted biaryls via solvent-mediated arylpalladium(II) reduction. Isotope labeling studies determined that the decomposition of 1,2-dimethoxyethane (DME) is indeed involved in the reductive process.
Jenn-Huei Lii et al.
Journal of computational chemistry, 24(12), 1490-1503 (2003-07-18)
Ethylene glycol, its dimethyl ether, and some related compounds have been studied using the MM4 molecular mechanics force field. The MM4 calculated structural and energetic results have been brought into satisfactory agreement with a considerable number of experimental data and

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