Sodium 1-octanesulfonate solution

suitable for ion pair chromatography, LiChropur, concentrate, ampule

1-Octanesulfonic acid sodium salt
Linear Formula:
CAS Number:
Molecular Weight:
Beilstein/REAXYS Number:
MDL number:
PubChem Substance ID:

Quality Level




ampule of 25 mL


HPLC: suitable
ion pair chromatography: suitable


in concentrate

UV absorption

λ: 210 nm Amax: 0.08
λ: 220 nm Amax: 0.05
λ: 230 nm Amax: 0.03
λ: 260 nm Amax: 0.02
λ: 500 nm Amax: 0.02


corresponds to standard for RP gradient test
corresponds to standard for filter test

SMILES string




InChI key


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General description

Concentrate for 6x1 L ready-to-use solution. Dilute contents of one ampule (~0.3 M) to 1 L with HPLC grade water to obtain a 0.005 M eluent solution.
Sodium 1-octanesulfonate monohydrate (NaOS) is an ion-pairing reagent.


NaOS has been used as ion-pairing reagent for ultra-high performance liquid chromatography (UPLC) analysis with photodiode array detection to estimate paraquat (methyl viologen) in tissue homogenate. It may also be used in determination of dopamine and its metabolites in brain microdialysates using liquid chromatography combined with electrospray ionization tandem mass spectrometry (LC–ESI-MS/MS).

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves


NONH for all modes of transport

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Rapid and simple analysis of paraquat in tissue homogenate by ultra-high performance liquid chromatography.
Merritt, T. J. S., et al.
Analytical Methods : Advancing Methods and Applications, 3.6, 1428-1432 (2011)
Kamila Syslová et al.
Journal of chromatography. A, 1218(21), 3382-3391 (2011-03-15)
A sensitive assay method was developed for a parallel, rapid and precise determination of dopamine and its metabolites, homovanillic acid, 3-methoxytyramine and 3,4-dihydroxyphenylacetic acid, from brain microdialysates. The method consisted of a pre-treatment step, freeze-drying (lyophilization), to concentrate dopamine and...
M T Veciana-Nogues et al.
Journal of AOAC International, 78(4), 1045-1050 (1995-07-01)
A liquid chromatographic method with postcolumn derivatization is described for determination of biogenic amines in fish and fish products. Histamine, tyramine, serotonin, beta-phenylethylamine, tryptamine, putrescine, cadaverine, agmatine, spermine, and spermidine can be determined in less than 60 min. Routine sample...
H T Jung et al.
Proceedings of the National Academy of Sciences of the United States of America, 98(4), 1353-1357 (2001-02-15)
Equilibrium unilamellar vesicles are stabilized by one of two distinct mechanisms depending on the value of the bending constant. Helfrich undulations ensure that the interbilayer potential is always repulsive when the bending constant, K, is of order k(B)T. When K...
W Xie et al.
Biochimica et biophysica acta, 1768(5), 1299-1308 (2007-03-14)
Perfluorooctanesulfonic acid (PFOS) is a persistent environmental pollutant that may cause adverse effects by inhibiting pulmonary surfactant. To gain further insights in this potential mechanism of toxicity, we investigated the interaction of PFOS potassium salt with dipalmitoylphosphatidylcholine (DPPC) - the...

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