75285

Supelco

N′-Nitrosonornicotine

analytical standard

Synonym(s):
1-Nitroso-2-(3-pyridyl)pyrrolidine, 3-(1-Nitroso-2-pyrrolidinyl)pyridine, NNN
Empirical Formula (Hill Notation):
C9H11N3O
CAS Number:
Molecular Weight:
177.20
MDL number:
PubChem Substance ID:
NACRES:
NA.24

Quality Level

grade

analytical standard

assay

≥99.0% (HPLC)

form

neat

shelf life

limited shelf life, expiry date on the label

application(s)

HPLC: suitable
gas chromatography (GC): suitable
solid phase extraction (SPE): suitable

Featured Industry

Cleaning Products
Cosmetics
Food and Beverages
Personal Care

format

neat

storage temp.

2-8°C

SMILES string

O=NN1CCCC1c2cccnc2

InChI

1S/C9H11N3O/c13-11-12-6-2-4-9(12)8-3-1-5-10-7-8/h1,3,5,7,9H,2,4,6H2

InChI key

XKABJYQDMJTNGQ-UHFFFAOYSA-N

General description

N′-Nitrosonornicotine is a tobacco specific nitrosamine, which is found to be carcinogenic in nature. It is produced via nitrosation of nicotine during the process of curing, aging, processing and smoking of tobacco.

Application

N′-Nitrosonornicotine may be used as an analytical reference standard for the quantification of the analyte in biological samples using liquid chromatography coupled with tandem mass spectrometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Statements

Precautionary Statements

hazcat

Acute Tox. 3 Oral - Carc. 2

storage_class_code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Sultana Shahana Banu et al.
International journal for parasitology, 49(7), 555-567 (2019-05-21)
In the Indian subcontinent, infection with Leishmania donovani can cause fatal visceral leishmaniasis. Genetic variation in L. donovani is believed to occur rapidly from environmental changes and through selective drug pressures, thereby allowing continued disease occurrence in this region. All...
Huda Mahmoud et al.
Frontiers in microbiology, 8, 2063-2063 (2017-11-09)
Corals that naturally thrive under extreme conditions are gaining increasing attention due to their importance as living models to understand the impact of global warming on world corals. Here, we present the first metagenomic study of viral communities in corals...
Julia Heger-Stevic et al.
PLoS pathogens, 14(12), e1007488-e1007488 (2018-12-20)
Hepatitis B virus (HBV) replicates its 3 kb DNA genome through capsid-internal reverse transcription, initiated by assembly of 120 core protein (HBc) dimers around a complex of viral pregenomic (pg) RNA and polymerase. Following synthesis of relaxed circular (RC) DNA...
Nat. Toxicology Program (NTP) (NIH)
Report on Carcinogens (12th Ed. ) (2011)
Théo Araújo-Santos et al.
Scientific reports, 7(1), 4334-4334 (2017-07-01)
Visceral leishmaniasis (VL) remains a major public health problem worldwide. Cytokine balance is thought to play a critical role in the development of this disease. Here, we perform a prospective exploratory study addressing whether simultaneous assessment of circulating levels of...

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