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Ginkgolic acid C15:1

analytical standard

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Synonym(s):
22:1-ω7-Anacardic acid, 6-[(8Z)-Pentadecenyl]-salicylic acid, Anacardic acid monoene, Ginkgolic acid I, Romanicardic acid
Empirical Formula (Hill Notation):
C22H34O3
CAS Number:
Molecular Weight:
346.50
MDL number:
PubChem Substance ID:

grade

analytical standard

Quality Level

assay

≥80% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

CCCCCC\C=C/CCCCCCCc1cccc(O)c1C(O)=O

InChI

1S/C22H34O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-17-15-18-20(23)21(19)22(24)25/h7-8,15,17-18,23H,2-6,9-14,16H2,1H3,(H,24,25)/b8-7-

InChI key

YXHVCZZLWZYHSA-FPLPWBNLSA-N

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General description

Ginkgolic acid C15:1 is an alkylphenol belonging to the class of ginkgolic acids isolated from Ginkgo biloba leaves. It also shows strong allergenic properties, with carcinogenic and mutagenic activity.

Application

Ginkgolic acid C15:1 may be used as a reference standard in the quantitative determination of alkylphenols like ginkgolic acids in Ginkgolic extract using high performance liquid chromatography coupled with mass spectrometry(HPLC-MS).
Ginkgolic acid C15:1 may be used as an analytical reference standard for the quantification of the analyte in Ginkgo biloba plant extracts, and dietary supplements using chromatography techniques.
Ginkgolic acid C15:1 may be used as a reference standard in the quantitative determination of alkylphenols like ginkgolic acids in Ginkgolic extract using high performance liquid chromatography coupled with mass spectrometry(HPLC-MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Aquatic Chronic 4 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

509.9 °F - (calculated)

flash_point_c

265.5 °C - (calculated)

ppe

dust mask type N95 (US), Eyeshields, Gloves


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T1503
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25G
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A simple HPLC-UV method for the assay of ginkgolic acids in Ginkgo biloba extracts
Fuzzati.N, et al.
Fitoterapia, 74(3), 247-256 (2003)
Concurrent supercritical fluid chromatographic analysis of terpene lactones and ginkgolic acids in Ginkgo biloba extracts and dietary supplements
Wang M, et al.
Analytical and Bioanalytical Chemistry, 408(17), 4649-4660 (2016)
P Loungratana et al.
The American journal of Chinese medicine, 32(1), 33-48 (2004-05-25)
A competitive enzyme-linked immunosorbent assay (ELISA) for ginkgolic acids (GAs) was developed using monoclonal antibody (MAb) 9F raised against 6-(13-formylheptyl) salicylic acid covalently coupled to bovine serum albumin (BSA). ELISA, at an effective measuring range of 300 ng/ml-1 microgram/ml of
Z H Liu et al.
Rapid communications in mass spectrometry : RCM, 23(13), 1899-1906 (2009-05-23)
Ginkgolic acids have been shown to possess allergenic as well as genotoxic and cytotoxic properties. The question arises whether the metabolism of ginkgolic acids in the liver could decrease or increase their toxicity. In this study, the in vitro metabolism
Chenchen Zhou et al.
Chemotherapy, 56(5), 393-402 (2010-10-16)
Ginkgolic acids (GAs), extracted from the seed coat of Ginkgo biloba L. Our previous study has shown that GA monomer could inhibit the growth of Hep-2 significantly and induce the fragmentation of the chromosomal DNA. To further assess the antitumor

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