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76887

Supelco

1,4-Dioxane

analytical standard

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Synonym(s):
Diethylene oxide, Dioxane
Empirical Formula (Hill Notation):
C4H8O2
CAS Number:
123-91-1
Molecular Weight:
88.11
Beilstein:
102551
EC Number:
204-661-8
MDL number:
MFCD00006571
PubChem Substance ID:
329767413
NACRES:
NA.24

grade

analytical standard

Quality Level

100

vapor density

3 (vs air)

vapor pressure

27 mmHg ( 20 °C)
40 mmHg ( 25 °C)

Assay

≥99.5% (GC)

autoignition temp.

356 °F

shelf life

limited shelf life, expiry date on the label

expl. lim.

22 %

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.422 (lit.)
n20/D 1.422

bp

100-102 °C (lit.)

mp

10-12 °C (lit.)

density

1.034 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

SMILES string

C1COCCO1

InChI

1S/C4H8O2/c1-2-6-4-3-5-1/h1-4H2

InChI key

RYHBNJHYFVUHQT-UHFFFAOYSA-N

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1 of 4

This Item
33147676934PHR1549
1,4-Dioxane analytical standard

Supelco

76887

1,4-Dioxane

1,4-Dioxane puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥99.5% (GC)

Sigma-Aldrich

33147

1,4-Dioxane

1,4-Dioxane ACS reagent, ≥99.0%

Sigma-Aldrich

676934

1,4-Dioxane

1,4-Dioxane Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1549

1,4-Dioxane

assay

≥99.5% (GC)

assay

≥99.5% (GC)

assay

≥99.0%

assay

-

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

thin layer chromatography (TLC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

application(s)

-

application(s)

-

application(s)

pharmaceutical (small molecule)

format

neat

format

-

format

-

format

neat

General description

1,4-Dioxane is an organic compound and an environmental contaminant, generally found in industrial waste streams and by-products. It is commonly used as an industrial solvent, in cosmetic products and household products such as lotions, soap, shampoos, bath foams.

Application

1,4-Dioxane may be used as an analytical reference standard for the quantification of the analyte in water samples using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

recommended

Product No.
Description
Pricing

Signal Word

Danger

Hazard Statements

H225 - H319 - H335 - H350

Hazard Classifications

Carc. 1B - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Respiratory system

Supplementary Hazards

EUH019 - EUH066

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

51.8 °F - closed cup

Flash Point(C)

11 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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T1503
Product Number
-
25G
Pack Size/Quantity

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705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

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1,4-Dioxane suitable for HPLC, ≥99.5%

Sigma-Aldrich

34857

1,4-Dioxane

1,4-Dioxane puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥99.5% (GC)

Sigma-Aldrich

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1,4-Dioxane

1,4-Dioxane-d8 ≥99 atom % D

Sigma-Aldrich

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1,4-Dioxane-d8

1,4-Dioxane ACS reagent, ≥99.0%, contains ≤25 ppm BHT as stabilizer

Sigma-Aldrich

360481

1,4-Dioxane

1,4-Dioxane ACS reagent, ≥99.0%

Sigma-Aldrich

676934

1,4-Dioxane

1,4-Dioxane solution NMR reference standard, 40% in benzene-d6 (99.6 atom % D), chromium(III) acetylacetonate 5 mg/mL, NMR tube size 3 mm × 8 in.

Sigma-Aldrich

612073

1,4-Dioxane solution

Trace-level determination of 1, 4-dioxane in water by isotopic dilution GC and GC-MS
Draper.MW, et al.
Analyst, 125(8), 1403-1408 (2008)
Simultaneous determination of 22 volatile organic compounds, methyl-tert-butyl ether, 1, 4-dioxane, 2-methylisoborneol and geosmin in water by headspace solid phase microextraction-gas chromatography-mass spectrometry
Nakamura S and Daishima S
Analytica Chimica Acta, 548(1-2), 79-85 (2005)
Xiaohua Liu et al.
Biomaterials, 31(2), 259-269 (2009-09-29)
It remains a challenge to synthesize functional materials that can develop advanced scaffolding architectures for tissue engineering. In this study, a series of biodegradable amphiphilic poly(hydroxyalkyl (meth)acrylate)-graft-poly(l-lactic acid) (PHAA-g-PLLA) copolymers have been synthesized and fabricated into nano-fibrous scaffolds. These copolymers
Astragaloside IV promotes the eNOS/NO/cGMP pathway and improves left ventricular diastolic function in rats with metabolic syndrome.
Xin Lin et al.
The Journal of international medical research, 48(1), 300060519826848-300060519826848 (2019-03-08)
Joshua J Pacheco et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(23), 8363-8367 (2014-06-10)
Terephthalic acid (PTA), a monomer in the synthesis of polyethylene terephthalate (PET), is obtained by the oxidation of petroleum-derived p-xylene. There is significant interest in the synthesis of renewable, biomass-derived PTA. Here, routes to PTA starting from oxidized products of
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