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77699

Sigma-Aldrich

2-Phenoxyethanol

≥99%

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Synonym(s):
Ethylene glycol monophenyl ether, PHE, PHE-G, PHE-S, PhG, Phenylglycol
Linear Formula:
C6H5OCH2CH2OH
CAS Number:
122-99-6
Molecular Weight:
138.16
Beilstein:
1364011
EC Number:
204-589-7
MDL number:
MFCD00002857
PubChem Substance ID:
329767877
NACRES:
NA.22

Quality Level

200

Assay

≥99%

form

viscous liquid

refractive index

n20/D 1.539

bp

244-246 °C

mp

11-13 °C

solubility

soluble, clear

density

1.107 g/mL at 20 °C (lit.)

SMILES string

OCCOc1ccccc1

InChI

1S/C8H10O2/c9-6-7-10-8-4-2-1-3-5-8/h1-5,9H,6-7H2

InChI key

QCDWFXQBSFUVSP-UHFFFAOYSA-N

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1 of 4

This Item
PHR1121567531526200
2-Phenoxyethanol ≥99%

Sigma-Aldrich

77699

2-Phenoxyethanol

2-Phenoxyethanol Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1121

2-Phenoxyethanol

2-Phenoxyethanol analytical standard

Supelco

56753

2-Phenoxyethanol

Phenoxyethanol United States Pharmacopeia (USP) Reference Standard

USP

1526200

Phenoxyethanol

form

viscous liquid

form

-

form

-

form

-

refractive index

n20/D 1.539

refractive index

-

refractive index

n20/D 1.539

refractive index

-

bp

244-246 °C

bp

244-246 °C

bp

244-246 °C

bp

244-246 °C

mp

11-13 °C

mp

11-13 °C

mp

11-13 °C

mp

11-13 °C

solubility

soluble, clear

solubility

-

solubility

-

solubility

-

General description

2-Phenoxyethanol is used as a fish anesthetic agent.

Application

2-Phenoxyethanol may be used as a starting material to synthesize diorganodiselenides derivatives. It can undergo aromatic alkylation with fluoren-9-one to form 9,9-bis[4-(2-hydroxyethoxy)phenyl]fluorene in the presence of Ti4+ cation-exchanged montmorillonite catalyst.

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302 - H318 - H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

258.8 °F - closed cup

Flash Point(C)

126 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Mehmet Çağrı Akgündüz et al.
Scientific reports, 10(1), 1209-1209 (2020-01-29)
In this study, the toxic effects of phenoxyethanol (Phy-Et), which is widely used in cosmetic industry, has been investigated with Allium test by means of physiological, cytogenetic, anatomical and biochemical parameters. To determine the changes in physiological reactions weight gain
Simple and clean synthesis of 9, 9-bis [4-(2-hydroxyethoxy) phenyl] fluorene from the aromatic alkylation of phenoxyethanol with fluoren-9-one catalysed by titanium cation-exchanged montmorillonite.
Ebitani K
Green Chemistry, 2(4), 157-160 (2000)
Anaesthetic qualities of eugenol and 2-phenoxyethanol and their effect on some haematological parameters in farmed European sea bass (Dicentrarchus labrax L.).
Filiciotto F
Journal of Animal and Veterinary Advances, 11, 494-502 (2012)
Catarina C V Oliveira et al.
International journal of molecular sciences, 21(23) (2020-12-03)
Kisspeptin regulates puberty and reproduction onset, acting upstream of the brain-pituitary-gonad (HPG) axis. This study aimed to test a kisspeptin-based hormonal therapy on cultured Senegalese sole (G1) breeders, known to have reproductive dysfunctions. A single intramuscular injection of KISS2-10 decapeptide
Efficacy of 2-phenoxyethanol as an anaesthetic for adult redline torpedo fish, Sahyadria denisonii (day 1865).
Varkey T
International Journal of Zoology (2014)
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